8V08
Crystal structure of human PLD4 co-crystallized with 5'Pi-ssDNA
Summary for 8V08
Entry DOI | 10.2210/pdb8v08/pdb |
Descriptor | 5'-3' exonuclease PLD4, ssDNA (3 entities in total) |
Functional Keywords | pld4, phospholipase, phosphohistidine, nuclease, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 109166.59 |
Authors | Yuan, M.,Wilson, I.A. (deposition date: 2023-11-17, release date: 2024-03-13, Last modification date: 2024-06-19) |
Primary citation | Yuan, M.,Peng, L.,Huang, D.,Gavin, A.,Luan, F.,Tran, J.,Feng, Z.,Zhu, X.,Matteson, J.,Wilson, I.A.,Nemazee, D. Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32:766-779.e7, 2024 Cited by PubMed: 38537643DOI: 10.1016/j.str.2024.02.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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