8V08

Crystal structure of human PLD4 co-crystallized with 5'Pi-ssDNA

Summary for 8V08

Entry DOI	10.2210/pdb8v08/pdb
Descriptor	5'-3' exonuclease PLD4, ssDNA (3 entities in total)
Functional Keywords	pld4, phospholipase, phosphohistidine, nuclease, hydrolase-dna complex, hydrolase/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	109166.59
Authors	Yuan, M.,Wilson, I.A. (deposition date: 2023-11-17, release date: 2024-03-13, Last modification date: 2024-04-17)
Primary citation	Yuan, M.,Peng, L.,Huang, D.,Gavin, A.,Luan, F.,Tran, J.,Feng, Z.,Zhu, X.,Matteson, J.,Wilson, I.A.,Nemazee, D. Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 2024 Cited by PubMed: 38537643 DOI: 10.1016/j.str.2024.02.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation