6AOS

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 3'-SLNLN

Summary for 6AOS

Entry DOI	10.2210/pdb6aos/pdb
Related PRD ID	PRD_900067
Descriptor	Hemagglutinin HA1 chain, Hemagglutinin HA2chain, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	influenza a virus, hemagglutinin, mutant, receptor binding, antigenicity, viral protein
Biological source	Influenza A virus (A/Brisbane/10/2007(H3N2)) More
Total number of polymer chains	2
Total formula weight	59196.69
Authors	Wu, N.C.,Wilson, I.A. (deposition date: 2017-08-16, release date: 2017-10-18, Last modification date: 2023-10-04)
Primary citation	Wu, N.C.,Zost, S.J.,Thompson, A.J.,Oyen, D.,Nycholat, C.M.,McBride, R.,Paulson, J.C.,Hensley, S.E.,Wilson, I.A. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. PLoS Pathog., 13:e1006682-e1006682, 2017 Cited by PubMed: 29059230 DOI: 10.1371/journal.ppat.1006682 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation