8V07
Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 30 days
Summary for 8V07
Entry DOI | 10.2210/pdb8v07/pdb |
Descriptor | 5'-3' exonuclease PLD3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | pld3, phospholipase, phosphohistidine, nuclease, hydrolase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 4 |
Total formula weight | 213731.08 |
Authors | Yuan, M.,Wilson, I.A. (deposition date: 2023-11-17, release date: 2024-03-13, Last modification date: 2024-06-19) |
Primary citation | Yuan, M.,Peng, L.,Huang, D.,Gavin, A.,Luan, F.,Tran, J.,Feng, Z.,Zhu, X.,Matteson, J.,Wilson, I.A.,Nemazee, D. Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32:766-779.e7, 2024 Cited by PubMed: 38537643DOI: 10.1016/j.str.2024.02.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
Download full validation report