6AOP

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant apo form

Summary for 6AOP

• Entry DOI: 10.2210/pdb6aop/pdb
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: influenza a virus, hemagglutinin, mutant, receptor binding, antigenicity, viral protein
• Biological source: Influenza A virus (A/Brisbane/10/2007(H3N2)); More
• Total number of polymer chains: 2
• Total formula weight: 58667.19

Authors

Wu, N.C.,Wilson, I.A. (deposition date: 2017-08-16, release date: 2017-10-18, Last modification date: 2023-10-04)

• Primary citation: Wu, N.C.,Zost, S.J.,Thompson, A.J.,Oyen, D.,Nycholat, C.M.,McBride, R.,Paulson, J.C.,Hensley, S.E.,Wilson, I.A.; A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.; PLoS Pathog., 13:e1006682-e1006682, 2017; PubMed: 29059230; DOI: 10.1371/journal.ppat.1006682

Experimental method

X-RAY DIFFRACTION (2.3 Å)