Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5ZVK

Crystal Structure of the Human Coronavirus MERS HR1 motif in complex with pan-CoVs inhibitor EK1

Summary for 5ZVK
Entry DOI10.2210/pdb5zvk/pdb
Related5zuv
DescriptorHuman Coronavirus MERS HR1 motif, pan-CoV inhibitory peptide EK1 (2 entities in total)
Functional Keywordsmers, spike protein, s2 domain, hr1 motif, pan-coronavirus, viral protein-inhibitor complex, viral protein/inhibitor
Biological sourceMiddle East respiratory syndrome-related coronavirus (MERS coronavirus, MERS-CoV)
More
Total number of polymer chains6
Total formula weight40455.20
Authors
Yan, L.,Yang, B.,Wilson, I.A. (deposition date: 2018-05-11, release date: 2019-04-10, Last modification date: 2023-11-22)
Primary citationXia, S.,Yan, L.,Xu, W.,Agrawal, A.S.,Algaissi, A.,Tseng, C.K.,Wang, Q.,Du, L.,Tan, W.,Wilson, I.A.,Jiang, S.,Yang, B.,Lu, L.
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike.
Sci Adv, 5:eaav4580-eaav4580, 2019
Cited by
PubMed: 30989115
DOI: 10.1126/sciadv.aav4580
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.31 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon