Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6MBU
DownloadVisualize
BU of 6mbu by Molmil
Crystal structure of wild-type KRAS (1-169) bound to GDP and Mg (Space group P3)
分子名称: GLYCEROL, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Dharmaiah, S, Tran, T.H, Yan, W, Simanshu, D.K.
登録日2018-08-30
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Sci Rep, 9, 2019
6WS2
DownloadVisualize
BU of 6ws2 by Molmil
Crystal structure of KRAS-K104Q mutant, GDP-bound
分子名称: CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tran, T.H, Simanshu, D.K.
登録日2020-04-30
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Allosteric regulation of switch-II domain controls KRAS oncogenicity.
Cancer Res., 2023
6WS4
DownloadVisualize
BU of 6ws4 by Molmil
Crystal structure of KRAS-G12D/K104Q mutant, GDP-bound
分子名称: 3,3',3''-phosphanetriyltripropanoic acid, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tran, T.H, Simanshu, D.K.
登録日2020-04-30
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Allosteric regulation of switch-II domain controls KRAS oncogenicity.
Cancer Res., 2023
6XHA
DownloadVisualize
BU of 6xha by Molmil
Crystal Structure of KRAS-G12V (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF
分子名称: CHLORIDE ION, GLYCEROL, Isoform 2B of GTPase KRas, ...
著者Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K.
登録日2020-06-18
公開日2021-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Nat Commun, 12, 2021
6XGV
DownloadVisualize
BU of 6xgv by Molmil
Crystal Structure of KRAS-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF
分子名称: CHLORIDE ION, GLYCEROL, GTPase KRas, ...
著者Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K.
登録日2020-06-18
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Nat Commun, 12, 2021
6XHB
DownloadVisualize
BU of 6xhb by Molmil
Crystal Structure of wild-type KRAS (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF (crystal form II)
分子名称: CHLORIDE ION, GLYCEROL, GTPase KRas, ...
著者Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K.
登録日2020-06-18
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Nat Commun, 12, 2021
6XGU
DownloadVisualize
BU of 6xgu by Molmil
Crystal Structure of KRAS-Q61R (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF
分子名称: GLYCEROL, GTPase KRas, MAGNESIUM ION, ...
著者Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K.
登録日2020-06-18
公開日2021-01-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Nat Commun, 12, 2021
3O7V
DownloadVisualize
BU of 3o7v by Molmil
Crystal Structure of human Hiwi1 (V361M) PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OCH3 at its 3'-end
分子名称: Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*(OMU))-3')
著者Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J.
登録日2010-08-01
公開日2011-01-12
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O6E
DownloadVisualize
BU of 3o6e by Molmil
Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OCH3 at its 3'-end
分子名称: Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*(OMU))-3')
著者Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J.
登録日2010-07-28
公開日2011-01-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.904 Å)
主引用文献Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O3I
DownloadVisualize
BU of 3o3i by Molmil
Crystal Structure of human Hiwi1 PAZ domain (residues 277-399) in complex with 14-mer RNA (12-bp + 2-nt overhang) containing 2'-OH at its 3'-end
分子名称: Piwi-like protein 1, RNA (5'-R(*GP*CP*GP*AP*AP*UP*AP*UP*UP*CP*GP*CP*UP*U)-3')
著者Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J.
登録日2010-07-24
公開日2011-01-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O7X
DownloadVisualize
BU of 3o7x by Molmil
Crystal structure of human Hili PAZ domain
分子名称: Piwi-like protein 2
著者Tian, Y, Simanshu, D.K, Ma, J.-B, Patel, D.J.
登録日2010-08-01
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9248 Å)
主引用文献Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q0B
DownloadVisualize
BU of 3q0b by Molmil
Crystal structure of SUVH5 SRA- fully methylated CG DNA complex in space group P42212
分子名称: DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3Q0F
DownloadVisualize
BU of 3q0f by Molmil
Crystal structure of SUVH5 SRA- methylated CHH DNA complex
分子名称: DNA (5'-D(*CP*TP*GP*AP*GP*GP*AP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*CP*TP*(5CM)P*CP*TP*CP*AP*G)-3'), Histone-lysine N-methyltransferase, ...
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
7LC2
DownloadVisualize
BU of 7lc2 by Molmil
Crystal Structure of KRAS4b-Q61R (GMPPNP-bound) in complex with the RAS-binding domain (RBD) of SIN1
分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Dharmaiah, S, Simanshu, D.K.
登録日2021-01-09
公開日2021-07-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LC1
DownloadVisualize
BU of 7lc1 by Molmil
Crystal Structure of KRAS4b (GMPPNP-bound) in complex with the RBD-PH domains of SIN1
分子名称: Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Dharmaiah, S, Simanshu, D.K.
登録日2021-01-09
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Proc.Natl.Acad.Sci.USA, 118, 2021
3Q0D
DownloadVisualize
BU of 3q0d by Molmil
Crystal structure of SUVH5 SRA- hemi methylated CG DNA complex
分子名称: CHLORIDE ION, DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*AP*(5CM)P*GP*TP*CP*AP*G)-3'), ...
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3704 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3Q0C
DownloadVisualize
BU of 3q0c by Molmil
Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122
分子名称: DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*TP*T)-3'), Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, ...
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6567 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3RIU
DownloadVisualize
BU of 3riu by Molmil
Crystal structure of Drosophila hexameric C3PO formed by truncated Translin and Trax
分子名称: Translin, Translin associated factor X, isoform B
著者Tian, Y, Simanshu, D.K, Patel, D.J.
登録日2011-04-14
公開日2011-05-11
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex.
Nat.Struct.Mol.Biol., 18, 2011
8STN
DownloadVisualize
BU of 8stn by Molmil
Crystal structure of KRAS-G12D/G75A mutant, GDP-bound
分子名称: CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tran, T.H, Dharmaiah, S, Simanshu, D.K.
登録日2023-05-10
公開日2023-08-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Cancer Res., 83, 2023
8STM
DownloadVisualize
BU of 8stm by Molmil
Crystal structure of KRAS-G75A mutant, GDP-bound
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Tran, T.H, Dharmaiah, S, Simanshu, D.K.
登録日2023-05-10
公開日2023-08-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Cancer Res., 83, 2023
8T73
DownloadVisualize
BU of 8t73 by Molmil
Crystal structure of KRAS4a-R151G with bound GDP and Mg ion
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K.
登録日2023-06-19
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
8T72
DownloadVisualize
BU of 8t72 by Molmil
Crystal structure of WT KRAS4a with bound GMPPNP and Mg ion
分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K.
登録日2023-06-19
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
8T75
DownloadVisualize
BU of 8t75 by Molmil
Crystal Structure of KRAS4a (GMPPNP) in complex with RAF1 (RBD-CRD)
分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Whitley, M.J, Simanshu, D.K.
登録日2023-06-19
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
8T74
DownloadVisualize
BU of 8t74 by Molmil
Crystal structure of KRAS4a (GMPPNP) in complex with RAF1 (RBD)
分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Whitley, M.J, Simanshu, D.K.
登録日2023-06-19
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024
8T71
DownloadVisualize
BU of 8t71 by Molmil
Crystal Structure of WT KRAS4a with bound GDP and Mg ion
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Tran, T.H, Whitley, M.J, Dharmaiah, S, Simanshu, D.K.
登録日2023-06-19
公開日2024-02-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Sci Adv, 10, 2024

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon