8DKB
 
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8GOU
 | | Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH003 Fab heavy chain, ... | | 著者 | Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z. | | 登録日 | 2022-08-25 | | 公開日 | 2023-06-28 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.
Nat Commun, 14, 2023
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8GPY
 | | Crystal structure of Omicron BA.4/5 RBD in complex with a neutralizing antibody scFv | | 分子名称: | Spike protein S1, scFv | | 著者 | Gao, Y.X, Song, Z.D, Wang, W.M, Guo, Y. | | 登録日 | 2022-08-27 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.
Nat Commun, 14, 2023
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4YT6
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4YT7
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7RX2
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7RXH
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7RXA
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7RX3
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7RXG
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7RWJ
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7RXB
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9B4J
 | | Filament of D-TLKIVWS, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | 分子名称: | DTH-DLE-DLY-DIL-DVA-DTR-DSN | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-20 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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9B4K
 | | Filament of D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | 分子名称: | DTH-DLE-DLY-DIL-DVA-DTR-DAR | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-20 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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9B4O
 | | Alzheimer's Tau Paired Helical Filaments, determined by CryoEM, before addition of D-peptide disaggregants | | 分子名称: | Microtubule-associated protein tau | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-21 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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9B4I
 | | Filament of D-TLKIVWI, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | 分子名称: | DTH-DLE-DLY-DIL-DVA-DTR-DIL | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-20 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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9B4N
 | | Filament of Tau in complex with D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | 分子名称: | Microtubule-associated protein tau | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-21 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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9B4M
 | | Filament of Tau in complex with D-TLKIVWS, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | 分子名称: | Microtubule-associated protein tau | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-20 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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9B4L
 | | Filament of Tau in complex with D-TLKIVWI, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | 分子名称: | DTH-DLE-DLY-DIL-DVA-DTR-DIL, Microtubule-associated protein tau, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID | | 著者 | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2024-03-20 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | How short peptides disassemble tau fibrils in Alzheimer's disease
Nature, 2025
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3NEW
 | | p38-alpha complexed with Compound 10 | | 分子名称: | 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, Mitogen-activated protein kinase 14 | | 著者 | Goedken, E.R, Comess, K.M, Sun, C, Argiriadi, M, Jia, Y, Quinn, C.M, Banach, D.L, Marcotte, D, Borhani, D. | | 登録日 | 2010-06-09 | | 公開日 | 2010-12-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases.
Acs Chem.Biol., 6, 2011
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3O17
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8K04
 | | CryoEM structure of a 2,3-hydroxycinnamic acid 1,2-dioxygenase MhpB in apo form | | 分子名称: | 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase | | 著者 | Jiang, W.X, Cheng, X.Q, Ma, L.X, Xing, Q. | | 登録日 | 2023-07-07 | | 公開日 | 2024-07-10 | | 最終更新日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Structural and catalytic insights into MhpB: A dioxygenase enzyme for degrading catecholic pollutants.
J Hazard Mater, 488, 2025
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4XIC
 | | ANTPHD WITH 15BP di-thioate modified DNA DUPLEX | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C2S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... | | 著者 | White, M.A, Zandarashvili, L, Iwahara, J. | | 登録日 | 2015-01-06 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Biophys.J., 109, 2015
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5VGU
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4X9J
 | | EGR-1 with Doubly Methylated DNA | | 分子名称: | DNA (5'-D(*AP*GP*(5CM)P*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*(5CM)P*GP*C)-3'), Early growth response protein 1, ... | | 著者 | White, M.A, Zandarashvili, L, Iwahara, J. | | 登録日 | 2014-12-11 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.412 Å) | | 主引用文献 | Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.
Febs Lett., 589, 2015
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