7RXB

afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+

Summary for 7RXB

Entry DOI	10.2210/pdb7rxb/pdb
Related	7RWJ
EMDB information	24717 24722 24723 24726 24727 24730 24731
Descriptor	afTMEM16 lipid scramblase, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (2 entities in total)
Functional Keywords	tmem16, lipid scrambling, lipid transport
Biological source	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
Total number of polymer chains	2
Total formula weight	175225.77
Authors	Feng, Z.,Accardi, A. (deposition date: 2021-08-22, release date: 2022-05-18, Last modification date: 2022-05-25)
Primary citation	Falzone, M.E.,Feng, Z.,Alvarenga, O.E.,Pan, Y.,Lee, B.,Cheng, X.,Fortea, E.,Scheuring, S.,Accardi, A. TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13:2604-2604, 2022 Cited by PubMed: 35562175 DOI: 10.1038/s41467-022-30300-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.07 Å)

Structure validation