7RXA
afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+
Summary for 7RXA
Entry DOI | 10.2210/pdb7rxa/pdb |
Related | 7RWJ |
EMDB information | 24717 24722 24723 24726 24727 24730 24731 |
Descriptor | afTMEM16 lipid scramblase, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (2 entities in total) |
Functional Keywords | tmem16, lipid scrambling, lipid transport |
Biological source | Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) |
Total number of polymer chains | 2 |
Total formula weight | 175021.68 |
Authors | Feng, Z.,Accardi, A. (deposition date: 2021-08-22, release date: 2022-05-18, Last modification date: 2024-06-05) |
Primary citation | Falzone, M.E.,Feng, Z.,Alvarenga, O.E.,Pan, Y.,Lee, B.,Cheng, X.,Fortea, E.,Scheuring, S.,Accardi, A. TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13:2604-2604, 2022 Cited by PubMed: 35562175DOI: 10.1038/s41467-022-30300-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.08 Å) |
Structure validation
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