7RXA
afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | afTMEM16 lipid scramblase | polymer | 735 | 84514.8 | 2 | UniProt (Q4WA18) Pfam (PF20877) Pfam (PF04547) | Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) | |
| 2 | C, D, E, F, G... (A, B) | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate | non-polymer | 749.0 | 8 | Chemie (PGW) |
Sequence modifications
A, B: 1 - 735 (UniProt: Q4WA18)
| PDB | External Database | Details |
|---|---|---|
| Ala 511 | Asp 511 | engineered mutation |
| Ala 514 | Glu 514 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 169029.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 5992.1 | |
| All* | Total formula weight | 175021.7 |
