7RWJ

afTMEM16 in C22 lipid nanodiscs with MSP2N2 scaffold protein in the presnece of Ca2+

Summary for 7RWJ

Entry DOI	10.2210/pdb7rwj/pdb
Related	7RX2 7RX3 7RXA 7RXB 7RXG 7RXH
EMDB information	24717 24722 24723 24726 24727 24730 24731
Descriptor	Plasma membrane channel protein (Aqy1), putative, CALCIUM ION, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (3 entities in total)
Functional Keywords	tmem16, lipid scrambling, lipid transport
Biological source	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Total number of polymer chains	2
Total formula weight	172390.06
Authors	Falzone, M.E.,Accardi, A. (deposition date: 2021-08-20, release date: 2022-05-18, Last modification date: 2022-06-01)
Primary citation	Falzone, M.E.,Feng, Z.,Alvarenga, O.E.,Pan, Y.,Lee, B.,Cheng, X.,Fortea, E.,Scheuring, S.,Accardi, A. TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13:2604-2604, 2022 Cited by PubMed: 35562175 DOI: 10.1038/s41467-022-30300-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation