8GPY

Crystal structure of Omicron BA.4/5 RBD in complex with a neutralizing antibody scFv

Summary for 8GPY

• Entry DOI: 10.2210/pdb8gpy/pdb
• Descriptor: Spike protein S1, scFv (3 entities in total)
• Functional Keywords: omicron, crystal strcture, neutralizing antibody, scfv, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 4
• Total formula weight: 94481.44

Authors

Gao, Y.X.,Song, Z.D.,Wang, W.M.,Guo, Y. (deposition date: 2022-08-27, release date: 2023-06-28, Last modification date: 2024-03-13)

• Primary citation: Guo, Y.,Zhang, G.,Yang, Q.,Xie, X.,Lu, Y.,Cheng, X.,Wang, H.,Liang, J.,Tang, J.,Gao, Y.,Shang, H.,Dai, J.,Shi, Y.,Zhou, J.,Zhou, J.,Guo, H.,Yang, H.,Qi, J.,Liu, L.,Ma, S.,Zhang, B.,Huo, Q.,Xie, Y.,Wu, J.,Dong, F.,Zhang, S.,Lou, Z.,Gao, Y.,Song, Z.,Wang, W.,Sun, Z.,Yang, X.,Xiong, D.,Liu, F.,Chen, X.,Zhu, P.,Wang, X.,Cheng, T.,Rao, Z.; Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.; Nat Commun, 14:3537-3537, 2023; PubMed: 37322000; DOI: 10.1038/s41467-023-39267-x

Experimental method

X-RAY DIFFRACTION (2.51 Å)