3MOM
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![BU of 3mom by Molmil](/molmil-images/mine/3mom) | Structure of holo HasAp H32A mutant complexed with imidazole from Pseudomonas aeruginosa to 2.25A Resolution | Descriptor: | Heme acquisition protein HasAp, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lovell, S, Battaile, K.P, Jepkorir, G, Rodriguez, J.C, Rui, H, Im, W, Alontaga, A.Y, Yukl, E, Moenne-Loccoz, P, Rivera, M. | Deposit date: | 2010-04-22 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural, NMR Spectroscopic, and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa. J.Am.Chem.Soc., 132, 2010
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3MOK
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![BU of 3mok by Molmil](/molmil-images/mine/3mok) | Structure of Apo HasAp from Pseudomonas aeruginosa to 1.55A Resolution | Descriptor: | Heme acquisition protein HasAp, PHOSPHATE ION, SODIUM ION | Authors: | Lovell, S, Battaile, K.P, Jepkorir, G, Rodriguez, J.C, Rui, H, Im, W, Alontaga, A.Y, Yukl, E, Moenne-Loccoz, P, Rivera, M. | Deposit date: | 2010-04-22 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural, NMR Spectroscopic, and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa. J.Am.Chem.Soc., 132, 2010
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3MOL
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![BU of 3mol by Molmil](/molmil-images/mine/3mol) | Structure of dimeric holo HasAp H32A Mutant from Pseudomonas aeruginosa to 1.20A Resolution | Descriptor: | Heme acquisition protein HasAp, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lovell, S, Battaile, K.P, Jepkorir, G, Rodriguez, J.C, Rui, H, Im, W, Alontaga, A.Y, Yukl, E, Moenne-Loccoz, P, Rivera, M. | Deposit date: | 2010-04-22 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural, NMR Spectroscopic, and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa. J.Am.Chem.Soc., 132, 2010
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8E4O
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![BU of 8e4o by Molmil](/molmil-images/mine/8e4o) | The closed C1-state mouse TRPM8 structure in complex with putative PI(4,5)P2 | Descriptor: | Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. | Deposit date: | 2022-08-18 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022
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8E4N
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![BU of 8e4n by Molmil](/molmil-images/mine/8e4n) | The closed C1-state mouse TRPM8 structure in complex with PI(4,5)P2 | Descriptor: | Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. | Deposit date: | 2022-08-18 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022
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8E4L
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![BU of 8e4l by Molmil](/molmil-images/mine/8e4l) | The open state mouse TRPM8 structure in complex with the cooling agonist C3, AITC, and PI(4,5)P2 | Descriptor: | 3-isothiocyanatoprop-1-ene, CALCIUM ION, Transient receptor potential cation channel subfamily M member 8, ... | Authors: | Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. | Deposit date: | 2022-08-18 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022
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8E4Q
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![BU of 8e4q by Molmil](/molmil-images/mine/8e4q) | The closed C0-state flycatcher TRPM8 structure in complex with PI(4,5)P2 | Descriptor: | Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. | Deposit date: | 2022-08-18 | Release date: | 2022-10-26 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022
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8E4P
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![BU of 8e4p by Molmil](/molmil-images/mine/8e4p) | Mouse TRPM8 structure determined in the ligand- and PI(4,5)P2-free condition, Class I , C0 state | Descriptor: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 8 | Authors: | Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. | Deposit date: | 2022-08-18 | Release date: | 2022-10-26 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022
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8E4M
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![BU of 8e4m by Molmil](/molmil-images/mine/8e4m) | The intermediate C2-state mouse TRPM8 structure in complex with the cooling agonist C3 and PI(4,5)P2 | Descriptor: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... | Authors: | Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y. | Deposit date: | 2022-08-18 | Release date: | 2022-10-26 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2. Science, 378, 2022
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6X7I
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![BU of 6x7i by Molmil](/molmil-images/mine/6x7i) | |
2JOW
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![BU of 2jow by Molmil](/molmil-images/mine/2jow) | Differences in the electrostatic surfaces of the type III secretion needle proteins | Descriptor: | Protein prgI | Authors: | Wang, Y, Ouellette, A.N, Egan, C.W, De Guzman, R.N. | Deposit date: | 2007-04-06 | Release date: | 2007-07-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Differences in the Electrostatic Surfaces of the Type III Secretion Needle Proteins PrgI, BsaL, and MxiH J.Mol.Biol., 371, 2007
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8ET7
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![BU of 8et7 by Molmil](/molmil-images/mine/8et7) | Cryo-EM structure of the organic cation transporter 1 in complex with diphenhydramine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, OCT1 | Authors: | Suo, Y, Wright, N.J, Lee, S.-Y. | Deposit date: | 2022-10-16 | Release date: | 2023-05-31 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nat.Struct.Mol.Biol., 30, 2023
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8ET8
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![BU of 8et8 by Molmil](/molmil-images/mine/8et8) | Cryo-EM structure of the organic cation transporter 1 in complex with verapamil | Descriptor: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1 | Authors: | Suo, Y, Wright, N.J, Lee, S.-Y. | Deposit date: | 2022-10-16 | Release date: | 2023-05-31 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nat.Struct.Mol.Biol., 30, 2023
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8ET9
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![BU of 8et9 by Molmil](/molmil-images/mine/8et9) | |
8ET6
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![BU of 8et6 by Molmil](/molmil-images/mine/8et6) | |
8TZ4
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![BU of 8tz4 by Molmil](/molmil-images/mine/8tz4) | Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter | Authors: | Wright, N.J, Lee, S.-Y. | Deposit date: | 2023-08-26 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024
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8TZD
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![BU of 8tzd by Molmil](/molmil-images/mine/8tzd) | |
8TZ2
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![BU of 8tz2 by Molmil](/molmil-images/mine/8tz2) | |
8TZ1
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![BU of 8tz1 by Molmil](/molmil-images/mine/8tz1) | |
8TZ7
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![BU of 8tz7 by Molmil](/molmil-images/mine/8tz7) | |
8TZ5
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![BU of 8tz5 by Molmil](/molmil-images/mine/8tz5) | |
8TZA
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![BU of 8tza by Molmil](/molmil-images/mine/8tza) | |
8TZ6
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![BU of 8tz6 by Molmil](/molmil-images/mine/8tz6) | |
8TZ3
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![BU of 8tz3 by Molmil](/molmil-images/mine/8tz3) | |
8TZ9
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![BU of 8tz9 by Molmil](/molmil-images/mine/8tz9) | |