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7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWM
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BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
4DDP
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BU of 4ddp by Molmil
crystal structure of Beclin 1 evolutionarily conserved domain(ECD)
Descriptor: Beclin-1
Authors:Huang, W.J, Choi, W.Y, Wang, J.W, Shi, Y.G.
Deposit date:2012-01-19
Release date:2012-02-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.547 Å)
Cite:Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
Cell Res., 2012
3PXG
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BU of 3pxg by Molmil
Structure of MecA121 and ClpC1-485 complex
Descriptor: Adapter protein mecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Wang, F, Mei, Z.Q, Wang, J.W, Shi, Y.G.
Deposit date:2010-12-09
Release date:2011-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.654 Å)
Cite:Structure and mechanism of the hexameric MecA-ClpC molecular machine.
Nature, 471, 2011
6DNH
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BU of 6dnh by Molmil
Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*C)-3'), ...
Authors:Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L.
Deposit date:2018-06-06
Release date:2018-06-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8HJV
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BU of 8hjv by Molmil
Cryo-EM structure of carotenoid-depleted RC-LH complex from Roseiflexus castenholzii at 10,000 lux
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ...
Authors:Xu, X, Xin, J.
Deposit date:2022-11-23
Release date:2023-09-20
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture.
Elife, 12, 2023
8HJU
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BU of 8hju by Molmil
Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 10,000 lux
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ...
Authors:Xu, X, Xin, J.
Deposit date:2022-11-23
Release date:2023-09-20
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture.
Elife, 12, 2023
6K7O
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BU of 6k7o by Molmil
Complex structure of LILRB4 and h128-3 antibody
Descriptor: Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain
Authors:Song, H, Chai, Y, Xu, X, Gao, F.G.
Deposit date:2019-06-08
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.
Cancer Immunol Res, 7, 2019
4F6O
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BU of 4f6o by Molmil
Crystal structure of the yeast metacaspase Yca1
Descriptor: 1,1-diphenylethanol, Metacaspase-1
Authors:Wong, A.H, Yan, C.Y, Shi, Y.G.
Deposit date:2012-05-15
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.681 Å)
Cite:Crystal structure of the yeast metacaspase Yca1.
J.Biol.Chem., 287, 2012
6JO7
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BU of 6jo7 by Molmil
Crystal structure of mouse MXRA8
Descriptor: Matrix remodeling-associated protein 8
Authors:Song, H, Zhao, Z, Qi, J, Gao, F, Gao, G.F.
Deposit date:2019-03-20
Release date:2019-05-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.
Cell, 177, 2019
6JO8
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BU of 6jo8 by Molmil
The complex structure of CHIKV envelope glycoprotein bound to human MXRA8
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHIKV E1, ...
Authors:Song, H, Zhao, Z, Qi, J, Gao, F, Gao, F.G.
Deposit date:2019-03-20
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.
Cell, 177, 2019
5ZI6
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BU of 5zi6 by Molmil
The RING domain structure of MEX-3C
Descriptor: RNA-binding E3 ubiquitin-protein ligase MEX3C, ZINC ION
Authors:Moududee, S.A, Tang, Y.
Deposit date:2018-03-14
Release date:2018-10-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional characterization of hMEX-3C Ring finger domain as an E3 ubiquitin ligase
Protein Sci., 27, 2018
5ZZ3
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BU of 5zz3 by Molmil
Crystal structure of intracellular B30.2 domain of BTN3A3
Descriptor: Butyrophilin, subfamily 3, member A3 isoform b variant
Authors:Yang, Y.Y, Li, X, Liu, W.D, Chen, C.C, Guo, R.T, Zhang, Y.H.
Deposit date:2018-05-30
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
5ZTM
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BU of 5ztm by Molmil
Crystal structure of MLE dsRBDs in complex with roX2 (R2H1)
Descriptor: Dosage compensation regulator, non-coding mRNA sequence roX2
Authors:Lv, M.Q, Tang, Y.J.
Deposit date:2018-05-04
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
Nucleic Acids Res., 47, 2019
1CSA
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BU of 1csa by Molmil
THE MUTANT E.COLI F112W CYCLOPHILIN BINDS CYCLOSPORIN A IN NEARLY IDENTICAL CONFORMATION AS HUMAN CYCLOPHILIN
Descriptor: CYCLOSPORIN A
Authors:Fejzo, J, Walsh, C.T, Wagner, G.
Deposit date:1992-02-24
Release date:1994-04-30
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:The Mutant Escherichia Coli F112W Cyclophilin Binds Cyclosporin a in Nearly Identical Conformation as Human Cyclophilin.
Biochemistry, 33, 1994
1D5R
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BU of 1d5r by Molmil
Crystal Structure of the PTEN Tumor Suppressor
Descriptor: L(+)-TARTARIC ACID, PHOSPHOINOSITIDE PHOSPHATASE PTEN
Authors:Lee, J.O, Yang, H, Georgescu, M.-M, Di Cristofano, A, Pavletich, N.P.
Deposit date:1999-10-11
Release date:1999-11-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Cell(Cambridge,Mass.), 99, 1999
6CF0
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BU of 6cf0 by Molmil
Sperm Whale Myoglobin H64V Mutant with Nitrite
Descriptor: GLYCEROL, Myoglobin, NITRITE ION, ...
Authors:Powell, S.M, Wang, B, Thomas, L.M, Richter-Addo, G.B.
Deposit date:2018-02-13
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and Quantum Mechanics and Molecular Mechanics Theoretical Investigations of Preferred Fe -NO Ligand Orientations in Myoglobin Distal Pockets.
Biochemistry, 57, 2018
8H9H
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BU of 8h9h by Molmil
Crystal structure of ZBTB7A in complex with GACCC-containing sequence
Descriptor: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ...
Authors:Yang, Y.
Deposit date:2022-10-25
Release date:2023-04-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4.
Febs J., 290, 2023
8T60
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BU of 8t60 by Molmil
CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
Descriptor: Melibiose permease, NabFab_H Chain, NabFab_L Chain, ...
Authors:Guan, L.
Deposit date:2023-06-14
Release date:2024-02-28
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter.
Elife, 12, 2024
1IOW
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BU of 1iow by Molmil
COMPLEX OF Y216F D-ALA:D-ALA LIGASE WITH ADP AND A PHOSPHORYL PHOSPHINATE
Descriptor: 1(S)-AMINOETHYL-(2-CARBOXYPROPYL)PHOSPHORYL-PHOSPHINIC ACID, ADENOSINE-5'-DIPHOSPHATE, D-ALA:D-ALA LIGASE, ...
Authors:Knox, J.R, Moews, P.C, Fan, C.
Deposit date:1996-09-20
Release date:1997-02-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:D-alanine:D-alanine ligase: phosphonate and phosphinate intermediates with wild type and the Y216F mutant.
Biochemistry, 36, 1997
4RDN
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BU of 4rdn by Molmil
Structure of YTH-YTHDF2 in complex with m6A
Descriptor: N-methyladenosine, SULFATE ION, YTH domain-containing family protein 2
Authors:Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y.
Deposit date:2014-09-19
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.
Cell Res., 24, 2014
8GOU
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BU of 8gou by Molmil
Omicron BA.4/5 SARS-CoV-2 S in complex with TH003 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, TH003 Fab heavy chain, ...
Authors:Guo, Y, Zhang, G, Liang, J, Liu, F, Rao, Z.
Deposit date:2022-08-25
Release date:2023-06-28
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.
Nat Commun, 14, 2023

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