4RDN

Structure of YTH-YTHDF2 in complex with m6A

Summary for 4RDN

• Entry DOI: 10.2210/pdb4rdn/pdb
• Related: 4RDO
• Descriptor: YTH domain-containing family protein 2, N-methyladenosine, SULFATE ION, ... (4 entities in total)
• Functional Keywords: m6a methylated rna binding, atypical beta-propeller, rna binding, m6a methylated rna, rna binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, P-body : Q9Y5A9
• Total number of polymer chains: 2
• Total formula weight: 39682.48

Authors

Li, F.D.,Zhao, D.B.,Wu, J.H.,Shi, Y.Y. (deposition date: 2014-09-19, release date: 2014-12-24, Last modification date: 2024-02-28)

• Primary citation: Li, F.,Zhao, D.,Wu, J.,Shi, Y.; Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition.; Cell Res., 24:1490-1492, 2014; PubMed: 25412658; DOI: 10.1038/cr.2014.153

Experimental method

X-RAY DIFFRACTION (2.1 Å)