8H9H

Crystal structure of ZBTB7A in complex with GACCC-containing sequence

Summary for 8H9H

• Entry DOI: 10.2210/pdb8h9h/pdb
• Descriptor: DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), Zinc finger and BTB domain-containing protein 7A, ... (5 entities in total)
• Functional Keywords: zbtb7a, primed to naive transition, transcription regulation, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 28445.67

Authors

Yang, Y. (deposition date: 2022-10-25, release date: 2023-04-26, Last modification date: 2023-11-29)

• Primary citation: Yang, Y.,Xiao, L.,Xue, Y.,Idris, M.O.,Liu, J.,Pei, D.,Shi, Y.,Liao, B.,Li, F.; ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4.; Febs J., 290:3896-3909, 2023; PubMed: 37013936; DOI: 10.1111/febs.16789

Experimental method

X-RAY DIFFRACTION (2.2 Å)