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6U2J
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BU of 6u2j by Molmil
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Pang, S.S, Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.37 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2W
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BU of 6u2w by Molmil
EM structure of MPEG-1(L425K) pre-pore complex bound to liposome
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Pang, S.S, Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U23
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BU of 6u23 by Molmil
EM structure of MPEG-1(w.t.) soluble pre-pore
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Pang, S.S, Bayly-Jones, C.
Deposit date:2019-08-19
Release date:2019-09-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2L
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BU of 6u2l by Molmil
EM structure of MPEG-1 (L425K, beta conformation) soluble pre-pore complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Pang, S.S, Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6U2K
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BU of 6u2k by Molmil
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Pang, S.S, Bayly-Jones, C.
Deposit date:2019-08-20
Release date:2019-09-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Nat Commun, 10, 2019
6VWI
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BU of 6vwi by Molmil
Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
Authors:Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
Deposit date:2020-02-19
Release date:2020-05-13
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
6WRU
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BU of 6wru by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Belousoff, M.J.
Deposit date:2020-04-30
Release date:2020-06-03
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6WRS
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BU of 6wrs by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Belousoff, M.J.
Deposit date:2020-04-30
Release date:2020-06-03
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6WVV
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BU of 6wvv by Molmil
Plasmodium vivax M17 leucyl aminopeptidase
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, M17 leucyl aminopeptidase, ...
Authors:Malcolm, T.R, Drinkwater, N, McGowan, S.
Deposit date:2020-05-07
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases.
J.Biol.Chem., 296, 2020
6WQN
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BU of 6wqn by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Belousoff, M.J.
Deposit date:2020-04-29
Release date:2020-06-03
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6XGP
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BU of 6xgp by Molmil
YSD1_17 major capsid protein
Descriptor: YSD1_17 major capsid protein
Authors:Grinter, R, Hardy, J.M, Dunstan, R, Lithgow, T.J, Coulibaly, F.J.
Deposit date:2020-06-17
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The architecture and stabilisation of flagellotropic tailed bacteriophages.
Nat Commun, 11, 2020
6WQQ
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BU of 6wqq by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Belousoff, M.J.
Deposit date:2020-04-29
Release date:2020-06-03
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
7U23
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BU of 7u23 by Molmil
Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form
Descriptor: Insulin-like growth factor 1 receptor, single-chain LCDV-1 viral insulin-like peptide
Authors:Kirk, N.S, Lawrence, M.C.
Deposit date:2022-02-22
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
Nat Commun, 13, 2022
7UAB
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BU of 7uab by Molmil
Human pro-meprin alpha (zymogen state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
Deposit date:2022-03-12
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAC
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BU of 7uac by Molmil
Human pro-meprin alpha (zymogen state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Meprin A subunit alpha, ...
Authors:Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
Deposit date:2022-03-12
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAE
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BU of 7uae by Molmil
Human meprin alpha (active state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
Deposit date:2022-03-12
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAF
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BU of 7uaf by Molmil
Human meprin alpha inhibitory complex with compound 10d (N~3~,N~3~-bis[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-beta-alaninamide)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
Deposit date:2022-03-12
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7UAI
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BU of 7uai by Molmil
Meprin alpha helix in complex with fetuin-B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
Deposit date:2022-03-13
Release date:2022-11-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Nat Commun, 13, 2022
7SYF
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BU of 7syf by Molmil
Reconstruction of full-length Prex-1 (PtdIns(3,4,5)P3-dependent Rac Exchanger 1)
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Endolysin chimera
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-11-24
Release date:2022-07-27
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.
Nat.Struct.Mol.Biol., 29, 2022
7JPT
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BU of 7jpt by Molmil
Structure of an endocytic receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 75, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Gully, B.S, Rossjohn, J, Berry, R.
Deposit date:2020-08-09
Release date:2020-12-09
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The cryo-EM structure of the endocytic receptor DEC-205.
J.Biol.Chem., 296, 2020
7JPU
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BU of 7jpu by Molmil
Structure of an endocytic receptor
Descriptor: Lymphocyte antigen 75
Authors:Gully, B.S, Rossjohn, J, Berry, R.
Deposit date:2020-08-09
Release date:2020-12-09
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The cryo-EM structure of the endocytic receptor DEC-205.
J.Biol.Chem., 296, 2020
7K5K
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BU of 7k5k by Molmil
Plasmodium vivax M17 leucyl aminopeptidase Pv-M17
Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, putative, ...
Authors:Malcolm, T.R, McGowan, S, Belousoff, M.J.
Deposit date:2020-09-17
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases.
J.Biol.Chem., 296, 2020
7LDJ
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BU of 7ldj by Molmil
SARS-CoV-2 receptor binding domain in complex with WNb-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 2, ...
Authors:Pymm, P, Dietrich, M.H, Tan, L.L, Adair, A, Tham, W.H.
Deposit date:2021-01-13
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:SARS-CoV-2 receptor binding domain in complex with WNb-2
Proc.Natl.Acad.Sci.USA, 2021
7LX5
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BU of 7lx5 by Molmil
The SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10
Descriptor: Spike glycoprotein, WNb 10, WNb 2
Authors:Pymm, P, Glukhova, A, Tham, W.-H.
Deposit date:2021-03-03
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MP5
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BU of 7mp5 by Molmil
Autoinhibited neurofibrobmin
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-04
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021

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