6WRU

Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid

Summary for 6WRU

Entry DOI	10.2210/pdb6wru/pdb
Related	6WQN 6WQQ 6WRS
EMDB information	21888
Descriptor	50S ribosomal protein L19, 50S ribosomal protein L29, 50S ribosomal protein L3, ... (29 entities in total)
Functional Keywords	antibiotic, tedizolid, oxazolidinone, ribosome
Biological source	Staphylococcus aureus More
Total number of polymer chains	28
Total formula weight	1315436.25
Authors	Belousoff, M.J. (deposition date: 2020-04-30, release date: 2020-06-03, Last modification date: 2020-12-16)
Primary citation	Wright, A.,Deane-Alder, K.,Marschall, E.,Bamert, R.,Venugopal, H.,Lithgow, T.,Lupton, D.W.,Belousoff, M.J. Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM. Acs Pharmacol Transl Sci, 3:425-432, 2020 Cited by PubMed: 32566908 DOI: 10.1021/acsptsci.0c00041 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation