7LX5

The SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10

Summary for 7LX5

• Entry DOI: 10.2210/pdb7lx5/pdb
• EMDB information: 23566
• Descriptor: Spike glycoprotein, WNb 2, WNb 10 (3 entities in total)
• Functional Keywords: sars-cov-2, nanobody cocktail, coronavirus spike, neutralizing nanobody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 3
• Total formula weight: 179956.32

Authors

Pymm, P.,Glukhova, A.,Tham, W.-H. (deposition date: 2021-03-03, release date: 2021-05-05)

• Primary citation: Pymm, P.,Adair, A.,Chan, L.J.,Cooney, J.P.,Mordant, F.L.,Allison, C.C.,Lopez, E.,Haycroft, E.R.,O'Neill, M.T.,Tan, L.L.,Dietrich, M.H.,Drew, D.,Doerflinger, M.,Dengler, M.A.,Scott, N.E.,Wheatley, A.K.,Gherardin, N.A.,Venugopal, H.,Cromer, D.,Davenport, M.P.,Pickering, R.,Godfrey, D.I.,Purcell, D.F.J.,Kent, S.J.,Chung, A.W.,Subbarao, K.,Pellegrini, M.,Glukhova, A.,Tham, W.H.; Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33893175; DOI: 10.1073/pnas.2101918118

Experimental method

ELECTRON MICROSCOPY (3.44 Å)