7LX5
The SARS-CoV-2 spike protein receptor binding domain bound to neutralizing nanobodies WNb 2 and WNb 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Spike glycoprotein | polymer | 1380 | 152312.8 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | B (C) | WNb 2 | polymer | 130 | 14106.6 | 1 | Vicugna pacos | ||
| 3 | C (A) | WNb 10 | polymer | 123 | 13537.0 | 1 | Vicugna pacos |
Sequence modifications
B: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met -91 | - | initiating methionine |
| Gly -90 | - | expression tag |
| Gly -89 | - | expression tag |
| Glu -88 | - | expression tag |
| Gly -87 | - | expression tag |
| Leu -86 | - | expression tag |
| Arg -85 | - | expression tag |
| Ala -84 | - | expression tag |
| Ser -83 | - | expression tag |
| Pro -82 | - | expression tag |
| Arg -81 | - | expression tag |
| Arg -80 | - | expression tag |
| Arg -79 | - | expression tag |
| Pro -78 | - | expression tag |
| Leu -77 | - | expression tag |
| Leu -76 | - | expression tag |
| Pro -75 | - | expression tag |
| Leu -74 | - | expression tag |
| Gln -73 | - | expression tag |
| Pro -72 | - | expression tag |
| Arg -71 | - | expression tag |
| Gly -70 | - | expression tag |
| Cys -69 | - | expression tag |
| Pro -68 | - | expression tag |
| Arg -67 | - | expression tag |
| Gly -66 | - | expression tag |
| Asp -65 | - | expression tag |
| Gly -64 | - | expression tag |
| Cys -63 | - | expression tag |
| Leu -62 | - | expression tag |
| Arg -61 | - | expression tag |
| Gly -60 | - | expression tag |
| Gly -59 | - | expression tag |
| Arg -58 | - | expression tag |
| Gly -57 | - | expression tag |
| Arg -56 | - | expression tag |
| Ala -55 | - | expression tag |
| Gly -54 | - | expression tag |
| Phe -53 | - | expression tag |
| Gly -52 | - | expression tag |
| Phe -51 | - | expression tag |
| Trp -50 | - | expression tag |
| Arg -49 | - | expression tag |
| Val -48 | - | expression tag |
| Thr -47 | - | expression tag |
| Gly -46 | - | expression tag |
| Gly -45 | - | expression tag |
| Ser -44 | - | expression tag |
| Ser -43 | - | expression tag |
| Ala -42 | - | expression tag |
| Ser -41 | - | expression tag |
| Ala -40 | - | expression tag |
| Asn -39 | - | expression tag |
| His -38 | - | expression tag |
| Val -37 | - | expression tag |
| His -36 | - | expression tag |
| Ala -35 | - | expression tag |
| Phe -34 | - | expression tag |
| Phe -33 | - | expression tag |
| Phe -32 | - | expression tag |
| Phe -31 | - | expression tag |
| Leu -30 | - | expression tag |
| Gln -29 | - | expression tag |
| Leu -28 | - | expression tag |
| Leu -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Asn -25 | - | expression tag |
| Val -24 | - | expression tag |
| Leu -23 | - | expression tag |
| Val -22 | - | expression tag |
| Val -21 | - | expression tag |
| Val -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| Phe -15 | - | expression tag |
| Gly -14 | - | expression tag |
| Lys -13 | - | expression tag |
| Glu -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gln -7 | - | expression tag |
| Ala -6 | - | expression tag |
| Glu -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Pro 817 | Phe 817 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Pro 942 | Ala 942 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
| Gly 1209 | - | expression tag |
| Ser 1210 | - | expression tag |
| Gly 1211 | - | expression tag |
| Tyr 1212 | - | expression tag |
| Ile 1213 | - | expression tag |
| Pro 1214 | - | expression tag |
| Glu 1215 | - | expression tag |
| Ala 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Arg 1218 | - | expression tag |
| Asp 1219 | - | expression tag |
| Gly 1220 | - | expression tag |
| Gln 1221 | - | expression tag |
| Ala 1222 | - | expression tag |
| Tyr 1223 | - | expression tag |
| Val 1224 | - | expression tag |
| Arg 1225 | - | expression tag |
| Lys 1226 | - | expression tag |
| Asp 1227 | - | expression tag |
| Gly 1228 | - | expression tag |
| Glu 1229 | - | expression tag |
| Trp 1230 | - | expression tag |
| Val 1231 | - | expression tag |
| Leu 1232 | - | expression tag |
| Leu 1233 | - | expression tag |
| Ser 1234 | - | expression tag |
| Thr 1235 | - | expression tag |
| Phe 1236 | - | expression tag |
| Leu 1237 | - | expression tag |
| Gly 1238 | - | expression tag |
| Arg 1239 | - | expression tag |
| Ser 1240 | - | expression tag |
| Leu 1241 | - | expression tag |
| Glu 1242 | - | expression tag |
| Val 1243 | - | expression tag |
| Leu 1244 | - | expression tag |
| Phe 1245 | - | expression tag |
| Gln 1246 | - | expression tag |
| Gly 1247 | - | expression tag |
| Pro 1248 | - | expression tag |
| Gly 1249 | - | expression tag |
| His 1250 | - | expression tag |
| His 1251 | - | expression tag |
| His 1252 | - | expression tag |
| His 1253 | - | expression tag |
| His 1254 | - | expression tag |
| His 1255 | - | expression tag |
| His 1256 | - | expression tag |
| His 1257 | - | expression tag |
| Ser 1258 | - | expression tag |
| Ala 1259 | - | expression tag |
| Trp 1260 | - | expression tag |
| Ser 1261 | - | expression tag |
| His 1262 | - | expression tag |
| Pro 1263 | - | expression tag |
| Gln 1264 | - | expression tag |
| Phe 1265 | - | expression tag |
| Glu 1266 | - | expression tag |
| Lys 1267 | - | expression tag |
| Gly 1268 | - | expression tag |
| Gly 1269 | - | expression tag |
| Gly 1270 | - | expression tag |
| Ser 1271 | - | expression tag |
| Gly 1272 | - | expression tag |
| Gly 1273 | - | expression tag |
| Gly 1274 | - | expression tag |
| Gly 1275 | - | expression tag |
| Ser 1276 | - | expression tag |
| Gly 1277 | - | expression tag |
| Gly 1278 | - | expression tag |
| Ser 1279 | - | expression tag |
| Ala 1280 | - | expression tag |
| Trp 1281 | - | expression tag |
| Ser 1282 | - | expression tag |
| His 1283 | - | expression tag |
| Pro 1284 | - | expression tag |
| Gln 1285 | - | expression tag |
| Phe 1286 | - | expression tag |
| Glu 1287 | - | expression tag |
| Lys 1288 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 179956.3 | |
| All* | Total formula weight | 179956.3 |
