3BOH
 
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 with acetate (CDCA1-R1) | | Descriptor: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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8FTU
 | | Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure | | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1 | | Authors: | Travis, S.M, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2023-01-13 | | Release date: | 2023-03-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (5.73 Å) | | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
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4CEV
 | | ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | | Descriptor: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | | Deposit date: | 1999-03-15 | | Release date: | 1999-04-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
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1FS2
 | | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | | Descriptor: | SKP1, SKP2 | | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | | Deposit date: | 2000-09-08 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
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1FS1
 | | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | | Descriptor: | CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45 | | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | | Deposit date: | 2000-09-08 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
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5VAE
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5VAF
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5BUZ
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5BV1
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7LTB
 | | Crystal Structure of Keratinicyclin B | | Descriptor: | (2~{S},4~{S},5~{R},6~{S})-4-azanyl-5-methoxy-6-methyl-oxan-2-ol, 3-ammonio-2,3,6-trideoxy-alpha-L-arabino-hexopyranose-(1-2)-beta-D-glucopyranose, FORMIC ACID, ... | | Authors: | Davis, K.M, Jeffrey, P.D, Seyedsayamdost, M.R. | | Deposit date: | 2021-02-19 | | Release date: | 2022-12-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Structural and Functional Analysis of Keratinicyclin Reveals Synergistic Antibiosis with Vancomycin against Clostridium difficile
to be published
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7LKC
 | | Crystal Structure of Keratinimicin A | | Descriptor: | (2~{S},4~{S},5~{R},6~{S})-4-azanyl-5-methoxy-6-methyl-oxan-2-ol, CHLORIDE ION, FORMIC ACID, ... | | Authors: | Davis, K.M, Jeffrey, P.D, Seyedsayamdost, M.R. | | Deposit date: | 2021-02-02 | | Release date: | 2022-12-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Structural and Functional Analysis of Keratinicyclin Reveals Synergistic Antibiosis with Vancomycin against Clostridium difficile
to be published
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7N29
 | | Structure of NAD kinase | | Descriptor: | NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. | | Deposit date: | 2021-05-28 | | Release date: | 2022-05-04 | | Last modified: | 2022-06-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria.
Proc.Natl.Acad.Sci.USA, 119, 2022
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2IE3
 | | Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins | | Descriptor: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | | Deposit date: | 2006-09-17 | | Release date: | 2006-11-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
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2HV6
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2IE4
 | | Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid | | Descriptor: | MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ... | | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | | Deposit date: | 2006-09-17 | | Release date: | 2006-11-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
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6CFI
 | | Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion | | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*(T64)P*TP*GP*GP*AP*TP*GP*TP*TP*GP*AP*GP*TP*CP*A)-3'), DNA repair protein RAD4, DNA('-D(*TP*TP*GP*AP*CP*TP*CP*AP*AP*CP*AP*TP*CP*CP*AP*AP*AP*GP*CP*TP*AP*CP*AP*A)-'), ... | | Authors: | Min, J, Jeffrey, P.D. | | Deposit date: | 2018-02-15 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.36241913 Å) | | Cite: | Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex.
Nucleic Acids Res., 47, 2019
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6D0H
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6D0I
 | | ParT: Prs ADP-ribosylating toxin bound to cognate antitoxin ParS. L48M ParT, SeMet-substituted complex. | | Descriptor: | GLYCEROL, ParS: COG5642 (DUF2384) antitoxin fragment, ParT: COG5654 (RES domain) toxin | | Authors: | Piscotta, F.J, Jeffrey, P.D, Link, A.J. | | Deposit date: | 2018-04-10 | | Release date: | 2019-01-09 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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8EKI
 | | CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1 | | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ... | | Authors: | DAmico, K.A, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2022-09-21 | | Release date: | 2023-10-04 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
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4H5I
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4I1A
 | | Crystal Structure of the Apo Form of RapI | | Descriptor: | CHLORIDE ION, Response regulator aspartate phosphatase I | | Authors: | Parashar, V, Jeffrey, P.D, Neiditch, M.B. | | Deposit date: | 2012-11-20 | | Release date: | 2013-04-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.443 Å) | | Cite: | Conformational change-induced repeat domain expansion regulates rap phosphatase quorum-sensing signal receptors.
Plos Biol., 11, 2013
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4I5K
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4H5J
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1MYK
 | | CRYSTAL STRUCTURE, FOLDING, AND OPERATOR BINDING OF THE HYPERSTABLE ARC REPRESSOR MUTANT PL8 | | Descriptor: | ARC REPRESSOR | | Authors: | Schildbach, J.F, Milla, M.E, Jeffrey, P.D, Raumann, B.E, Sauer, R.T. | | Deposit date: | 1994-10-12 | | Release date: | 1995-01-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure, folding, and operator binding of the hyperstable Arc repressor mutant PL8.
Biochemistry, 34, 1995
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1PI1
 | | Crystal structure of a human Mob1 protein; toward understanding Mob-regulated cell cycle pathways. | | Descriptor: | Mob1A, ZINC ION | | Authors: | Stavridi, E.S, Harris, K.G, Huyen, Y, Bothos, J, Voewerd, P.M, Stayrook, S.E, Jeffrey, P.D, Pavletich, N.P, Luca, F.C. | | Deposit date: | 2003-05-29 | | Release date: | 2003-09-30 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a human mob1 protein. Toward understanding mob-regulated cell cycle pathways.
Structure, 11, 2003
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