Structure of USP14 bound to ubquitin aldehyde

Summary for 2AYO

DescriptorUbiquitin carboxyl-terminal hydrolase 14, Ubiquitin (2 entities in total)
Functional Keywordsdeubiquitinating enzyme, dub, usp14, proteasome, enzyme mechanism, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P54578
Total number of polymer chains2
Total molecular weight54771.21
Hu, M.,Li, P.,Jeffrey, P.D.,Shi, Y. (deposition date: 2005-09-07, release date: 2005-10-18, Last modification date: 2011-07-13)
Primary citation
Hu, M.,Li, P.,Song, L.,Jeffrey, P.D.,Chenova, T.A.,Wilkinson, K.D.,Cohen, R.E.,Shi, Y.
Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.
Embo J., 24:3747-3756, 2005
PubMed: 16211010 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600832
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers639.9%15.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report