5EP2

Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor

Summary for 5EP2

• Entry DOI: 10.2210/pdb5ep2/pdb
• Related: 5EP0 5EP1 5EP3 5EP4
• Descriptor: Putative repressor protein luxO, 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, ... (4 entities in total)
• Functional Keywords: quorum sensing, aaa+ protein, catalytic domain, atpase, inhibitor, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• Biological source: Photobacterium angustum
• Total number of polymer chains: 1
• Total formula weight: 29063.11

Authors

Shah, T.,Selcuk, H.B.,Jeffrey, P.D.,Hughson, F.M. (deposition date: 2015-11-11, release date: 2016-04-20, Last modification date: 2024-03-06)

• Primary citation: Boyaci, H.,Shah, T.,Hurley, A.,Kokona, B.,Li, Z.,Ventocilla, C.,Jeffrey, P.D.,Semmelhack, M.F.,Fairman, R.,Bassler, B.L.,Hughson, F.M.; Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.; Plos Biol., 14:e1002464-e1002464, 2016; PubMed: 27219477; DOI: 10.1371/journal.pbio.1002464

Experimental method

X-RAY DIFFRACTION (1.421 Å)