1FQV

Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex

Summary for 1FQV

Related1fs1 1fs2
DescriptorSKP2, SKP1 (2 entities in total)
Functional Keywordsskp1, skp2, f-box, lrr, leucine-rich repeat, scf, ubiquitin, e3, ubiquitin protein ligase, ligase
Biological sourceHomo sapiens (human)
Total number of polymer chains16
Total molecular weight438214.84
Authors
Schulman, B.A.,Carrano, A.C.,Jeffrey, P.D.,Bowen, Z.,Kinnucan, E.R.,Finnin, M.S.,Elledge, S.J.,Harper, J.W.,Pagano, M.,Pavletich, N.P. (deposition date: 2000-09-06, release date: 2000-11-29, Last modification date: 2011-07-13)
Primary citation
Schulman, B.A.,Carrano, A.C.,Jeffrey, P.D.,Bowen, Z.,Kinnucan, E.R.,Finnin, M.S.,Elledge, S.J.,Harper, J.W.,Pagano, M.,Pavletich, N.P.
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408:381-386, 2000
PubMed: 11099048 (PDB entries with the same primary citation)
DOI: 10.1038/35042620
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers36 2.5% 4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02