1FQV

Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex

Summary for 1FQV

Entry DOI	10.2210/pdb1fqv/pdb
Related	1fs1 1fs2
Descriptor	SKP2, SKP1 (2 entities in total)
Functional Keywords	skp1, skp2, f-box, lrr, leucine-rich repeat, scf, ubiquitin, e3, ubiquitin protein ligase, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	16
Total formula weight	438214.84
Authors	Schulman, B.A.,Carrano, A.C.,Jeffrey, P.D.,Bowen, Z.,Kinnucan, E.R.,Finnin, M.S.,Elledge, S.J.,Harper, J.W.,Pagano, M.,Pavletich, N.P. (deposition date: 2000-09-06, release date: 2000-11-29, Last modification date: 2024-02-07)
Primary citation	Schulman, B.A.,Carrano, A.C.,Jeffrey, P.D.,Bowen, Z.,Kinnucan, E.R.,Finnin, M.S.,Elledge, S.J.,Harper, J.W.,Pagano, M.,Pavletich, N.P. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408:381-386, 2000 Cited by PubMed: 11099048 DOI: 10.1038/35042620 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation