1FQV

Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	SKP2	polymer	336	37923.7	8	UniProt (Q13309) Pfam (PF12937)	Homo sapiens (human)	CYCLIN A/CDK2-ASSOCIATED PROTEIN P45
2	B, D, F, H, J... (B, D, F, H, J...)	SKP1	polymer	149	16853.2	8	UniProt (P63208) Pfam (PF03931) Pfam (PF01466)	Homo sapiens (human)	CYCLIN A/CDK2-ASSOCIATED PROTEIN P19

Sequence modifications

B, D, F, H, J, L, N, P: 1 - 163 (UniProt: P63208)

PDB	External Database	Details
-	Asp 37	deletion
-	Asp 38	deletion
-	Glu 39	deletion
-	Gly 40	deletion
-	Asp 41	deletion
-	Asp 42	deletion
-	Pro 70	deletion
-	Pro 71	deletion
-	Pro 72	deletion
-	Glu 73	deletion
-	Asp 74	deletion
-	Asp 75	deletion
-	Glu 76	deletion
-	Asn 77	deletion
-	Lys 78	deletion
-	Glu 79	deletion
-	Lys 80	deletion
-	Arg 81	deletion
-	Thr 82	deletion
Gly 78	-	SEE REMARK 999
Gly 79	-	SEE REMARK 999
Ser 80	-	SEE REMARK 999
Gly 81	-	SEE REMARK 999
Thr 82	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	438214.8
All*	Total formula weight	438214.8

*Water molecules are not included.