2IE3

Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins

Summary for 2IE3

• Entry DOI: 10.2210/pdb2ie3/pdb
• Related: 2IE4
• Related PRD ID: PRD_000212
• Descriptor: Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, microcystin LR, ... (4 entities in total)
• Functional Keywords: heat repeat, signaling protein, hydrolase-toxin complex, hydrolase/toxin
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P67775
• Total number of polymer chains: 3
• Total formula weight: 102152.60

Authors

Xing, Y.,Xu, Y.,Chen, Y.,Jeffrey, P.D.,Chao, Y.,Shi, Y. (deposition date: 2006-09-17, release date: 2006-11-07, Last modification date: 2023-11-15)

• Primary citation: Xing, Y.,Xu, Y.,Chen, Y.,Jeffrey, P.D.,Chao, Y.,Lin, Z.,Li, Z.,Strack, S.,Stock, J.B.,Shi, Y.; Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins; Cell(Cambridge,Mass.), 127:341-353, 2006; PubMed: 17055435; DOI: 10.1016/j.cell.2006.09.025

Experimental method

X-RAY DIFFRACTION (2.8 Å)