1FS2
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Summary for 1FS2
Entry DOI | 10.2210/pdb1fs2/pdb |
Related | 1FQV 1FS1 |
Descriptor | SKP2, SKP1 (2 entities in total) |
Functional Keywords | skp1, skp2, f-box, lrrs, leucine-rich repeats, scf, ubiquitin, e3, ubiquitin protein ligase, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 93569.22 |
Authors | Schulman, B.A.,Carrano, A.C.,Jeffrey, P.D.,Bowen, Z.,Kinnucan, E.R.E.,Finnin, M.S.,Elledge, S.J.,Harper, J.W.,Pagano, M.,Pavletich, N.P. (deposition date: 2000-09-08, release date: 2000-11-29, Last modification date: 2024-02-07) |
Primary citation | Schulman, B.A.,Carrano, A.C.,Jeffrey, P.D.,Bowen, Z.,Kinnucan, E.R.,Finnin, M.S.,Elledge, S.J.,Harper, J.W.,Pagano, M.,Pavletich, N.P. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408:381-386, 2000 Cited by PubMed: 11099048DOI: 10.1038/35042620 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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