7XIK
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![BU of 7xik by Molmil](/molmil-images/mine/7xik) | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex | Descriptor: | B38 Fab heavy chain, B38 Fab light chain, Spike protein S1 | Authors: | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | Deposit date: | 2022-04-13 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex To Be Published
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7XIL
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![BU of 7xil by Molmil](/molmil-images/mine/7xil) | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B38 Fab heavy chain, B38 Fab light chain, ... | Authors: | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | Deposit date: | 2022-04-13 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex To Be Published
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8RE4
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![BU of 8re4 by Molmil](/molmil-images/mine/8re4) | |
8RED
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![BU of 8red by Molmil](/molmil-images/mine/8red) | |
8REE
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![BU of 8ree by Molmil](/molmil-images/mine/8ree) | |
8REC
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![BU of 8rec by Molmil](/molmil-images/mine/8rec) | |
8REA
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![BU of 8rea by Molmil](/molmil-images/mine/8rea) | |
8REB
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![BU of 8reb by Molmil](/molmil-images/mine/8reb) | |
8R64
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![BU of 8r64 by Molmil](/molmil-images/mine/8r64) | |
7YE6
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![BU of 7ye6 by Molmil](/molmil-images/mine/7ye6) | BAM-EspP complex structure with BamA-N427C/EspP-R1297C mutations in nanodisc | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly. Nature, 617, 2023
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7YE4
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![BU of 7ye4 by Molmil](/molmil-images/mine/7ye4) | BAM-EspP complex structure with BamA-G431C and G781C/EspP-N1293C and A1043C mutations in nanodisc | Descriptor: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | Authors: | Shen, C, Chang, S, Luo, Q, Zhang, Z, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhang, X, Tang, X, Dong, H. | Deposit date: | 2022-07-05 | Release date: | 2023-07-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly. Nature, 617, 2023
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6S8F
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![BU of 6s8f by Molmil](/molmil-images/mine/6s8f) | Structure of nucleotide-bound Tel1/ATM | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | Authors: | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | Deposit date: | 2019-07-09 | Release date: | 2019-10-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28, 2020
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5IJB
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![BU of 5ijb by Molmil](/molmil-images/mine/5ijb) | The ligand-free structure of the mouse TLR4/MD-2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | Authors: | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | Deposit date: | 2016-03-01 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
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8QOT
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![BU of 8qot by Molmil](/molmil-images/mine/8qot) | Structure of the mu opioid receptor bound to the antagonist nanobody NbE | Descriptor: | Anti-Fab Nanobody, Mu-type opioid receptor, NabFab HC, ... | Authors: | Yu, J, Kumar, A, Zhang, X, Martin, C, Raia, P, Manglik, A, Ballet, S, Boland, A, Stoeber, M. | Deposit date: | 2023-09-29 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist. Biorxiv, 2023
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8KD5
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![BU of 8kd5 by Molmil](/molmil-images/mine/8kd5) | Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2 | Descriptor: | 187bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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8KD7
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![BU of 8kd7 by Molmil](/molmil-images/mine/8kd7) | Rpd3S in complex with nucleosome with H3K36MLA modification and 167bp DNA | Descriptor: | 167bp DNA, Chromatin modification-related protein EAF3, Histone H2A, ... | Authors: | Dong, S, Li, H, Wang, M, Rasheed, N, Zou, B, Gao, X, Guan, J, Li, W, Zhang, J, Wang, C, Zhou, N, Shi, X, Li, M, Zhou, M, Huang, J, Li, H, Zhang, Y, Wong, K.H, Chang, X, Chao, W.C.H, He, J. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex. Cell Res., 33, 2023
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4TOR
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![BU of 4tor by Molmil](/molmil-images/mine/4tor) | Crystal structure of Tankyrase 1 with IWR-8 | Descriptor: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | Authors: | Chen, H, Zhang, X, Lum, L, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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5IJD
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![BU of 5ijd by Molmil](/molmil-images/mine/5ijd) | The crystal structure of mouse TLR4/MD-2/lipid A complex | Descriptor: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | Deposit date: | 2016-03-01 | Release date: | 2016-04-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
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5V6E
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5V6T
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![BU of 5v6t by Molmil](/molmil-images/mine/5v6t) | The Plexin D1 intracellular region in complex with GIPC1 | Descriptor: | PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION | Authors: | Shang, G, Zhang, X. | Deposit date: | 2017-03-17 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.189 Å) | Cite: | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
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4TOS
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![BU of 4tos by Molmil](/molmil-images/mine/4tos) | Crystal structure of Tankyrase 1 with 355 | Descriptor: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | Authors: | Chen, H, Zhang, X, Lum, l, Chen, C. | Deposit date: | 2014-06-06 | Release date: | 2015-05-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35, 2015
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5IJC
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![BU of 5ijc by Molmil](/molmil-images/mine/5ijc) | The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ... | Authors: | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | Deposit date: | 2016-03-01 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
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7V26
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![BU of 7v26 by Molmil](/molmil-images/mine/7v26) | XG005-bound SARS-CoV-2 S | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XG005 Heavy chain, ... | Authors: | Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G. | Deposit date: | 2021-08-07 | Release date: | 2021-10-20 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope. Protein Cell, 13, 2022
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7V1N
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![BU of 7v1n by Molmil](/molmil-images/mine/7v1n) | Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI | Descriptor: | Isoform Beta of Tissue factor pathway inhibitor, Toxin B | Authors: | Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L. | Deposit date: | 2021-08-05 | Release date: | 2022-02-23 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile. Cell, 185, 2022
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5V6B
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![BU of 5v6b by Molmil](/molmil-images/mine/5v6b) | Crystal structure of GIPC1 | Descriptor: | PDZ domain-containing protein GIPC1 | Authors: | Shang, G, Zhang, X. | Deposit date: | 2017-03-16 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
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