4TOS
Crystal structure of Tankyrase 1 with 355
Summary for 4TOS
Entry DOI | 10.2210/pdb4tos/pdb |
Related | 4TOR |
Descriptor | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 54437.24 |
Authors | |
Primary citation | Kulak, O.,Chen, H.,Holohan, B.,Wu, X.,He, H.,Borek, D.,Otwinowski, Z.,Yamaguchi, K.,Garofalo, L.A.,Ma, Z.,Wright, W.,Chen, C.,Shay, J.W.,Zhang, X.,Lum, L. Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells. Mol.Cell.Biol., 35:2425-2435, 2015 Cited by PubMed: 25939383DOI: 10.1128/MCB.00392-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.802 Å) |
Structure validation
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