4TOS

Crystal structure of Tankyrase 1 with 355

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
B	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1401

Chain	Residue
A	CYS1234
A	HIS1237
A	CYS1242
A	CYS1245

---

site_id	AC2
Number of Residues	21
Details	binding site for residue 355 A 1402

Chain	Residue
A	ILE1192
A	LYS1195
A	GLY1196
A	PHE1197
A	ASP1198
A	HIS1201
A	ALA1202
A	GLY1205
A	MET1207
A	GLY1211
A	TYR1213
A	LYS1220
A	TYR1224
A	GLY1227
A	HOH1536
A	HOH1605
A	HIS1184
A	GLY1185
A	SER1186
A	PRO1187
A	ALA1191

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 2000

Chain	Residue
B	CYS1234
B	HIS1237
B	CYS1242
B	CYS1245

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:18436240, ECO:0007744|PDB:2RF5, ECO:0007744|PDB:3UDD, ECO:0007744|PDB:3UH2, ECO:0007744|PDB:3UH4, ECO:0007744|PDB:4DVI, ECO:0007744|PDB:4I9I, ECO:0007744|PDB:4K4E, ECO:0007744|PDB:4K4F, ECO:0007744|PDB:4KRS, ECO:0007744|PDB:4LI6, ECO:0007744|PDB:4LI8, ECO:0007744|PDB:4MSG, ECO:0007744|PDB:4MSK, ECO:0007744|PDB:4MT9, ECO:0007744|PDB:4N3R, ECO:0007744|PDB:4N4V, ECO:0007744|PDB:4OA7, ECO:0007744|PDB:4TOR, ECO:0007744|PDB:4TOS, ECO:0007744|PDB:4W5S, ECO:0007744|PDB:4W6E

Chain	Residue	Details
A	CYS1234
A	HIS1237
A	CYS1242
A	CYS1245
B	CYS1234
B	HIS1237
B	CYS1242
B	CYS1245

---