6S8F

Structure of nucleotide-bound Tel1/ATM

Summary for 6S8F

Entry DOI	10.2210/pdb6s8f/pdb
EMDB information	10120
Descriptor	Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total)
Functional Keywords	kinase, dna damage response, cryoem, phosphatidylinositol-3-kinase-like kinase, hydrolase
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Total number of polymer chains	2
Total formula weight	586219.81
Authors	Yates, L.A.,Williams, R.M.,Ayala, R.,Zhang, X. (deposition date: 2019-07-09, release date: 2019-10-30, Last modification date: 2020-01-15)
Primary citation	Yates, L.A.,Williams, R.M.,Hailemariam, S.,Ayala, R.,Burgers, P.,Zhang, X. Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28:96-104.e3, 2020 Cited by PubMed: 31740029 DOI: 10.1016/j.str.2019.10.012 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation