8QOT

Structure of the mu opioid receptor bound to the antagonist nanobody NbE

Summary for 8QOT

• Entry DOI: 10.2210/pdb8qot/pdb
• EMDB information: 18541
• Descriptor: Mu-type opioid receptor, Nanobody E (NbE), NabFab HC, ... (5 entities in total)
• Functional Keywords: opioid receptor, nanobody, antagonist, nabfab, mor, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 5
• Total formula weight: 143882.64

Authors

Yu, J.,Kumar, A.,Zhang, X.,Martin, C.,Raia, P.,Manglik, A.,Ballet, S.,Boland, A.,Stoeber, M. (deposition date: 2023-09-29, release date: 2023-12-27)

• Primary citation: Yu, J.,Kumar, A.,Zhang, X.,Martin, C.,Raia, P.,Koehl, A.,Laeremans, T.,Steyaert, J.,Manglik, A.,Ballet, S.,Boland, A.,Stoeber, M.; Structural Basis of mu-Opioid Receptor-Targeting by a Nanobody Antagonist.; Biorxiv, 2023; PubMed: 38106026; DOI: 10.1101/2023.12.06.570395

Experimental method

ELECTRON MICROSCOPY (3.2 Å)