6C80
| Crystal structure of a flax cytokinin oxidase | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wan, L, Williams, S, Kobe, B. | Deposit date: | 2018-01-23 | Release date: | 2018-06-20 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural and functional insights into the modulation of the activity of a flax cytokinin oxidase by flax rust effector AvrL567-A. Mol. Plant Pathol., 20, 2019
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5JMV
| Crystal structure of mjKae1-pfuPcc1 complex | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein, ... | Authors: | Wan, L, Sicheri, F. | Deposit date: | 2016-04-29 | Release date: | 2016-07-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.3864696 Å) | Cite: | Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis. Nucleic Acids Res., 44, 2016
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4C6S
| Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RRS1 | Descriptor: | GLYCEROL, PROBABLE WRKY TRANSCRIPTION FACTOR 52, SODIUM ION, ... | Authors: | Wan, L, Williams, S.J, Sohn, K.H, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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5J26
| Crystal structure of a 53BP1 Tudor domain in complex with a ubiquitin variant | Descriptor: | Tumor suppressor p53-binding protein 1, Ubiquitin Variant i53 | Authors: | Wan, L, Canny, M, Juang, Y.C, Durocher, D, Sicheri, F. | Deposit date: | 2016-03-29 | Release date: | 2016-12-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.5047 Å) | Cite: | A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing To Be Published
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7D0Y
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7D0X
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7E4E
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6M6K
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6M6J
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7YF7
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6VP0
| Human Diacylglycerol Acyltransferase 1 in complex with oleoyl-CoA | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Diacylglycerol O-acyltransferase 1, Lauryl Maltose Neopentyl Glycol, ... | Authors: | Wang, L, Qian, H, Han, Y, Nian, Y, Ren, Z, Zhang, H, Hu, L, Prasad, B.V.V, Yan, N, Zhou, M. | Deposit date: | 2020-02-01 | Release date: | 2020-05-13 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature, 581, 2020
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6PE0
| Msp1 (E214Q)-substrate complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Membrane-spanning ATPase-like protein, ... | Authors: | Wang, L, Myasnikov, A, Pan, X, Walter, P. | Deposit date: | 2019-06-19 | Release date: | 2020-02-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife, 9, 2020
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6PDY
| Msp1-substrate complex in open conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Wang, L, Myasnikov, A, Pan, X, Walter, P. | Deposit date: | 2019-06-19 | Release date: | 2020-02-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. Elife, 9, 2020
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3RDZ
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4X67
| Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions. | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Wang, L, Chong, J, Wang, D. | Deposit date: | 2014-12-07 | Release date: | 2015-02-04 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions. Proc.Natl.Acad.Sci.USA, 112, 2015
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4X6A
| Crystal structure of yeast RNA polymerase II encountering oxidative Cyclopurine DNA lesions | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Wang, L, Chong, J, Wang, D. | Deposit date: | 2014-12-07 | Release date: | 2015-02-04 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.96 Å) | Cite: | Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions. Proc.Natl.Acad.Sci.USA, 112, 2015
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8TQO
| Eukaryotic translation initiation factor 2B tetramer | Descriptor: | Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit epsilon, ... | Authors: | Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P. | Deposit date: | 2023-08-08 | Release date: | 2023-12-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat.Chem.Biol., 20, 2024
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8TQZ
| Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit | Descriptor: | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... | Authors: | Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P. | Deposit date: | 2023-08-08 | Release date: | 2023-12-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat.Chem.Biol., 20, 2024
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2LKT
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3MCE
| Crystal structure of the NAC domain of alpha subunit of nascent polypeptide-associated complex(NAC) | Descriptor: | IODIDE ION, Nascent polypeptide-associated complex subunit alpha | Authors: | Wang, L.F, Zhang, W.C, Wang, L, Zhang, X.J.C, Li, X.M, Rao, Z. | Deposit date: | 2010-03-29 | Release date: | 2010-07-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit Protein Cell, 1, 2010
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3MCB
| Crystal structure of NAC domains of human nascent polypeptide-associated complex (NAC) | Descriptor: | IODIDE ION, Nascent polypeptide-associated complex subunit alpha, Transcription factor BTF3 | Authors: | Wang, L.F, Zhang, W.C, Wang, L, Zhang, X.J.C, Li, X.M, Rao, Z. | Deposit date: | 2010-03-29 | Release date: | 2010-07-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit Protein Cell, 1, 2010
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6WM2
| Human V-ATPase in state 1 with SidK and ADP | Descriptor: | (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, L, Wu, H, Fu, T.M. | Deposit date: | 2020-04-20 | Release date: | 2020-11-11 | Last modified: | 2020-11-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. Mol.Cell, 80, 2020
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4Y7N
| The Structure Insight into 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation. | Descriptor: | DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, L, Chong, J, Wang, D. | Deposit date: | 2015-02-15 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature, 523, 2015
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6WLW
| The Vo region of human V-ATPase in state 1 (focused refinement) | Descriptor: | (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, L, Wu, H, Fu, T.-M. | Deposit date: | 2020-04-20 | Release date: | 2020-11-11 | Last modified: | 2020-11-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. Mol.Cell, 80, 2020
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4Y52
| Crystal structure of 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation. | Descriptor: | DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, L, Chong, J, Wang, D. | Deposit date: | 2015-02-11 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature, 523, 2015
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