2LKT

Solution structure of N-terminal domain of human TIG3 in 2 M UREA

Summary for 2LKT

• Entry DOI: 10.2210/pdb2lkt/pdb
• NMR Information: BMRB: 18012
• Descriptor: Retinoic acid receptor responder protein 3 (1 entity in total)
• Functional Keywords: tig3, human tumor suppressor ii family, nlpc/p60, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 14050.89

Authors

Wang, L.,Yu, W.,Xia, B. (deposition date: 2011-10-21, release date: 2012-10-24, Last modification date: 2024-05-01)

Primary citation

Wang, L.,Yu, W.,Ren, X.,Lin, J.,Jin, C.,Xia, B.
(1)H, (13)C, and (15)N resonance assignments of the N-terminal domain of human TIG3
Biomol.Nmr Assign., 6:201-203, 2012

PubMed Abstract: Human TIG3 protein is a member of H-REV107 protein family which belongs to the type II tumor suppressor family. TIG3 can induce apoptosis in cancer cells, and it also possesses Ca(2+)-independent phospholipase A(1/2) activity. The NMR assignments of the N-terminal domain of TIG3 are essential for its solution structure determination.

PubMed: 22290676
DOI: 10.1007/s12104-012-9357-2

Experimental method

SOLUTION NMR