2XXM

Crystal structure of the HIV-1 capsid protein C-terminal domain in complex with a camelid VHH and the CAI peptide.

Summary for 2XXM

• Entry DOI: 10.2210/pdb2xxm/pdb
• Related: 1A43 1A8O 1AFV 1AK4 1AUM 1B92 1B9D 1B9F 1BAJ 1BHL 1BI4 1BIS 1BIU 1BIZ 1BL3 1GWP 1HIW 1ITG 1K6Y 1M9D 1QS4 1UPH 1WJB 1WJD 1WKN 2B4J 2H3F 2H3I 2H3Q 2H3V 2H3Z 2HMX 2HVP 2ITG 2X2D 2XT1 2XV6 2XXC 4PHV 5HVP 9HVP
• Descriptor: CAPSID PROTEIN P24, CAMELID VHH 9, INHIBITOR OF CAPSID ASSEMBLY, ... (5 entities in total)
• Functional Keywords: immune system-peptide complex, capsid inhibitor, protein binding, protein interface, virus assembly, immune system/peptide
• Biological source: HUMAN IMMUNODEFICIENCY VIRUS (HIV-1); More
• Total number of polymer chains: 3
• Total formula weight: 23195.03

Authors

Igonet, S.,Vaney, M.C.,Bartonova, V.,Helma, J.,Rothbauer, U.,Leonhardt, H.,Stura, E.,Krausslich, H.-G.,Rey, F.A. (deposition date: 2010-11-10, release date: 2011-10-12, Last modification date: 2023-12-20)

• Primary citation: Igonet, S.,Vaney, M.C.,Bartonova, V.,Helma, J.,Rothbauer, U.,Leonhardt, H.,Stura, E.,Krausslich, H.-G.,Rey, F.A.; Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors; To be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)