1BIS
HIV-1 INTEGRASE CORE DOMAIN
Summary for 1BIS
Entry DOI | 10.2210/pdb1bis/pdb |
Descriptor | HIV-1 INTEGRASE (2 entities in total) |
Functional Keywords | dna integration, integrase, hiv, hydrolase, aspartyl protease, endonuclease |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497 |
Total number of polymer chains | 2 |
Total formula weight | 36269.29 |
Authors | Goldgur, Y.,Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Craigie, R.,Davies, D.R. (deposition date: 1998-06-19, release date: 1998-08-19, Last modification date: 2024-05-22) |
Primary citation | Goldgur, Y.,Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Craigie, R.,Davies, D.R. Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proc.Natl.Acad.Sci.USA, 95:9150-9154, 1998 Cited by PubMed: 9689049DOI: 10.1073/pnas.95.16.9150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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