1BIU

HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++

Summary for 1BIU

DescriptorHIV-1 INTEGRASE, MAGNESIUM ION (3 entities in total)
Functional Keywordsdna integration, integrase, hiv, hydrolase, aspartyl protease, endonuclease
Biological sourceHuman immunodeficiency virus 1
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential) P12497
Total number of polymer chains3
Total molecular weight54443.83
Authors
Goldgur, Y.,Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Craigie, R.,Davies, D.R. (deposition date: 1998-06-19, release date: 1998-08-19, Last modification date: 2011-07-13)
Primary citation
Goldgur, Y.,Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Craigie, R.,Davies, D.R.
Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95:9150-9154, 1998
PubMed: 9689049 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.95.16.9150
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers7 0.5% 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170172
PDB entries from 2020-10-21