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2H3V

Structure of the HIV-1 Matrix protein bound to di-C8-phosphatidylinositol-(4,5)-bisphosphate

Summary for 2H3V
Entry DOI10.2210/pdb2h3v/pdb
Related2h3f 2h3i 2h3q 2h3z
DescriptorGag polyprotein, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (2 entities in total)
Functional Keywordshiv-1 unmyristoylated ma protein, viral protein
Biological sourceHuman immunodeficiency virus 1
Cellular locationMatrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
Total number of polymer chains1
Total formula weight15481.18
Authors
Saad, J.S.,Miller, J.,Tai, J.,Kim, A.,Ghanam, R.H.,Summers, M.F. (deposition date: 2006-05-23, release date: 2006-07-25, Last modification date: 2022-03-09)
Primary citationSaad, J.S.,Miller, J.,Tai, J.,Kim, A.,Ghanam, R.H.,Summers, M.F.
Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.
Proc.Natl.Acad.Sci.Usa, 103:11364-11369, 2006
Cited by
PubMed: 16840558
DOI: 10.1073/pnas.0602818103
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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