2H3Z

Structure of the HIV-1 matrix protein bound to di-C4-phosphatidylinositol-(4,5)-bisphosphate

Summary for 2H3Z

• Entry DOI: 10.2210/pdb2h3z/pdb
• Related: 2H3F 2H3I 2H3Q 2H3V
• Descriptor: Gag polyprotein, (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1,2-DIYL DIBUTANOATE (2 entities in total)
• Functional Keywords: hiv-1 unmyristoylated matrix protein, viral protein
• Biological source: Human immunodeficiency virus 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• Total number of polymer chains: 1
• Total formula weight: 15368.97

Authors

Saad, J.S.,Miller, J.,Tai, J.,Kim, A.,Ghanam, R.H.,Summers, M.F. (deposition date: 2006-05-23, release date: 2006-07-25, Last modification date: 2014-01-29)

• Primary citation: Saad, J.S.,Miller, J.,Tai, J.,Kim, A.,Ghanam, R.H.,Summers, M.F.; Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.; Proc.Natl.Acad.Sci.Usa, 103:11364-11369, 2006; PubMed: 16840558; DOI: 10.1073/pnas.0602818103

Experimental method

SOLUTION NMR