2XV6

Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 220) in complex with a camelid VHH.

Summary for 2XV6

Related2XXM 2XT1 2XXC
DescriptorCAPSID PROTEIN P24, CAMELID VHH 9 (3 entities in total)
Functional Keywordsviral protein-immune system complex, viral protein/immune system
Biological sourceHUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1)
More
Total number of polymer chains4
Total molecular weight43338.89
Authors
Igonet, S.,Vaney, M.C.,Bartonova, V.,Helma, J.,Rothbauer, U.,Leonhardt, H.,Stura, E.,Krausslich, H.-G.,Rey, F.A. (deposition date: 2010-10-22, release date: 2011-10-12, Last modification date: 2019-08-14)
Primary citation
Igonet, S.,Vaney, M.C.,Bartonova, V.,Helma, J.,Rothbauer, U.,Leonhardt, H.,Stura, E.,Krausslich, H.-G.,Rey, F.A.
Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
To be Published,
Experimental method
X-RAY DIFFRACTION (1.89 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19630 0.7% 4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution