1BHL

CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE

Summary for 1BHL

Entry DOI	10.2210/pdb1bhl/pdb
Descriptor	HIV-1 INTEGRASE (2 entities in total)
Functional Keywords	dna integration, aids, polyprotein, hydrolase, endonuclease, polynucleotidyl transferase, dna binding (viral)
Biological source	Human immunodeficiency virus 1
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
Total number of polymer chains	1
Total formula weight	16756.84
Authors	Maignan, S.,Guilloteau, J.P.,Zhou-Liu, Q.,Clement-Mella, C.,Mikol, V. (deposition date: 1998-06-10, release date: 1998-10-14, Last modification date: 2023-08-02)
Primary citation	Maignan, S.,Guilloteau, J.P.,Zhou-Liu, Q.,Clement-Mella, C.,Mikol, V. Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282:359-368, 1998 Cited by PubMed: 9735293 DOI: 10.1006/jmbi.1998.2002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation