4PHV
X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY
Summary for 4PHV
| Entry DOI | 10.2210/pdb4phv/pdb |
| Descriptor | HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE (3 entities in total) |
| Functional Keywords | hydrolase(aspartic proteinase) |
| Biological source | Human immunodeficiency virus 1 |
| Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497 |
| Total number of polymer chains | 2 |
| Total formula weight | 22899.08 |
| Authors | Bone, R. (deposition date: 1991-10-04, release date: 1993-10-31, Last modification date: 2024-02-28) |
| Primary citation | Bone, R.,Vacca, J.P.,Anderson, P.S.,Holloway, M.K. X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry J.Am.Chem.Soc., 113:9382-, 1991 Cited by |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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