4PHV

X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	HIV-1 PROTEASE	polymer	99	10830.8	2	UniProt (P12497) Pfam (PF00077)	Human immunodeficiency virus 1
2	C, D (B)	N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE	non-polymer		618.8	2	Chemie (VAC)
3	E, F (A, B)	water	water		18.0	104	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21661.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1237.5
All*	Total formula weight	22899.1

*Water molecules are not included.