1B92

MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY

Summary for 1B92

DescriptorPROTEIN (INTEGRASE), CACODYLATE ION, SULFATE ION, ... (4 entities in total)
Functional Keywordsdna integration, transferase
Biological sourceHuman immunodeficiency virus
Cellular locationGag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion  P12497
Total number of polymer chains1
Total molecular weight18296.55
Authors
Greenwald, J.,Le, V.,Butler, S.L.,Bushman, F.D.,Choe, S. (deposition date: 1999-02-19, release date: 1999-07-19, Last modification date: 2018-03-14)
Primary citation
Greenwald, J.,Le, V.,Butler, S.L.,Bushman, F.D.,Choe, S.
The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity.
Biochemistry, 38:8892-8898, 1999
PubMed: 10413462 (PDB entries with the same primary citation)
DOI: 10.1021/bi9907173
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.02 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers1201.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-07-29