2HVP

THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1

Summary for 2HVP

Entry DOI	10.2210/pdb2hvp/pdb
Descriptor	HIV-1 PROTEASE (1 entity in total)
Functional Keywords	hydrolase(acid proteinase)
Biological source	Human immunodeficiency virus 1
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
Total number of polymer chains	1
Total formula weight	10830.78
Authors	Navia, M.A.,Fitzgerald, P.M.D.,Mckeever, B.M.,Springer, J.P. (deposition date: 1989-04-10, release date: 1989-04-19, Last modification date: 2024-02-14)
Primary citation	Navia, M.A.,Fitzgerald, P.M.,McKeever, B.M.,Leu, C.T.,Heimbach, J.C.,Herber, W.K.,Sigal, I.S.,Darke, P.L.,Springer, J.P. Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1. Nature, 337:615-620, 1989 Cited by PubMed: 2645523 DOI: 10.1038/337615a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation