Structure of native TcAChE after a 9 seconds annealing to room temperature during the first 5 seconds of which laser irradiation at 266nm took place

Summary for 2VA9

Related1DX6 1E66 1EA5 1GPK 1GPN 1H22 1H23 1JGA 1JGB 1JJB 1QID 1QIG 1QIH 1QII 1ACJ 1ACL 1AMN 1AX9 1CFJ 1E3Q 1EEA 1EVE 1FSS 1GQR 1GQS 1HBJ 1OCE 1ODC 1QIE 1QIF 1QIJ 1QIK 1QIM 1QTI 1U65 1UT6 1VOT 1W6R 1W75 1ZGC 2ACE 2ACK 2C58 2C5F 2C5G 2CEK 2J3D 2V96 4ACE 1SOM 1VXO 1VXR 1W4L 1W76 1ZGB 2C4H 2CKM 2CMF 2DFP 2J3Q 2J4F 2V97 2V98 3ACE
DescriptorACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordspartial q-weighted difference refinement, neurotransmitter degradation, alternative splicing, kinetic crystallography, serine esterase, caged compounds, acetylcholinesterase, synapse, membrane, backdoor, hydrolase, gpi-anchor, lipoprotein, glycoprotein, cell junction
Total number of polymer chains2
Total molecular weight122357.86
Colletier, J.-P.,Sanson, B.,Royant, A.,Specht, A.,Nachon, F.,Masson, P.,Zaccai, G.,Sussman, J.L.,Goeldner, M.,Silman, I.,Bourgeois, D.,Weik, M. (deposition date: 2007-08-30, release date: 2007-11-20, Last modification date: 2020-07-29)
Primary citation
Colletier, J.-P.,Royant, A.,Specht, A.,Sanson, B.,Nachon, F.,Masson, P.,Zaccai, G.,Sussman, J.L.,Goeldner, M.,Silman, I.,Bourgeois, D.,Weik, M.
Use of a 'Caged' Analog to Study Traffic of Choline within Acetylcholinesterase by Kinetic Crystallography
Acta Crystallogr.,Sect.D, 63:1115-, 2007
PubMed: 18007027 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444907044472
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24822 0.2% 3.1% 1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16