1VOT

ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH HUPERZINE A

Summary for 1VOT

Entry DOI	10.2210/pdb1vot/pdb
Descriptor	ACETYLCHOLINESTERASE, Huperzine A (3 entities in total)
Functional Keywords	hydrolase, neurotransmitter cleavage
Biological source	Torpedo californica (Pacific electric ray)
Cellular location	Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058
Total number of polymer chains	1
Total formula weight	60978.83
Authors	Raves, M.L.,Harel, M.,Silman, I.,Sussman, J.L. (deposition date: 1996-06-23, release date: 1997-06-16, Last modification date: 2023-08-09)
Primary citation	Raves, M.L.,Harel, M.,Pang, Y.P.,Silman, I.,Kozikowski, A.P.,Sussman, J.L. Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A. Nat.Struct.Biol., 4:57-63, 1997 Cited by PubMed: 8989325 DOI: 10.1038/nsb0197-57 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation