2OJU

X-ray structure of complex of human cyclophilin J with cyclosporin A

Summary for 2OJU

• Entry DOI: 10.2210/pdb2oju/pdb
• Related: 1BCK 1C5F 1CSA 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1CYA 1CYB 1CYN 1M63 1MF8 1MIK 1QNG 1QNH 1XQ7 2ESL 2POY 2RMA 2RMB 2RMC 2WFJ 2X2C 2X7K 2Z6W 3BO7 3CYS 3EOV
• Related PRD ID: PRD_000142
• Descriptor: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3, CYCLOSPORIN A (3 entities in total)
• Functional Keywords: isomerase-immunosuppressant complex, cyclophilin-cyclosporin complex, cyclosporin a, immunosuppressant, cyclophilin, isomerase/immunosuppressant
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 39941.54

Authors

Xia, Z.,Huang, L. (deposition date: 2007-01-14, release date: 2008-01-22, Last modification date: 2023-11-15)

• Primary citation: Chen, J.,Chen, S.,Huang, L.,Zhao, X.,Tan, J.,Huang, C.,Saiyin, H.,Zhang, M.,Zeng, X.,Xi, J.,Wan, B.,Zhao, Y.,Xia, Z.,Jiang, H.,Yi, Q.,Liu, J.O.,Yu, L.; Targeting Cyclophilin J, a Novel Peptidyl-Prolyl Isomerase, Can Induce Cellular G1/S Arrest and Repress the Growth of Hepatocellular Carcinoma; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)