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1AGQ
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GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT
Descriptor: GLIAL CELL-DERIVED NEUROTROPHIC FACTOR
Authors:Eigenbrot, C, Gerber, N.
Deposit date:1997-03-25
Release date:1997-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding.
Nat.Struct.Biol., 4, 1997
1BMP
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BONE MORPHOGENETIC PROTEIN-7
Descriptor: BONE MORPHOGENETIC PROTEIN-7
Authors:Griffith, D.L, Scott, D.L.
Deposit date:1995-12-14
Release date:1997-07-23
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily.
Proc.Natl.Acad.Sci.USA, 93, 1996
1ES7
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COMPLEX BETWEEN BMP-2 AND TWO BMP RECEPTOR IA ECTODOMAINS
Descriptor: BONE MORPHOGENETIC PROTEIN RECEPTOR IA, BONE MORPHOGENETIC PROTEIN-2
Authors:Kirsch, T, Sebald, W, Dreyer, M.K.
Deposit date:2000-04-07
Release date:2000-10-07
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the BMP-2-BRIA ectodomain complex.
Nat.Struct.Biol., 7, 2000
1KLA
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SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES
Descriptor: TRANSFORMING GROWTH FACTOR-BETA 1
Authors:Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
Deposit date:1996-01-16
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLC
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SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: TRANSFORMING GROWTH FACTOR-BETA 1
Authors:Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
Deposit date:1996-01-16
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLD
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SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES
Descriptor: TRANSFORMING GROWTH FACTOR-BETA 1
Authors:Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
Deposit date:1996-01-16
Release date:1996-08-17
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KTZ
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Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3
Descriptor: TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3
Authors:Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P.
Deposit date:2002-01-18
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.
Nat.Struct.Biol., 9, 2002
1LX5
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Crystal Structure of the BMP7/ActRII Extracellular Domain Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin Type II Receptor, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Greenwald, J, Groppe, J, Kwiatkowski, W, Choe, S.
Deposit date:2002-06-04
Release date:2003-04-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
Mol.Cell, 11, 2003
1LXI
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Refinement of BMP7 crystal structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BONE MORPHOGENETIC PROTEIN 7
Authors:Greenwald, J, Groppe, J, Kwiatkowski, W, Choe, S.
Deposit date:2002-06-05
Release date:2003-04-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
Mol.Cell, 11, 2003
1M4U
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Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone Morphogenetic Protein-7, Noggin
Authors:Groppe, J, Greenwald, J, Wiater, E, Rodriguez-Leon, J, Economides, A.N, Kwiatkowski, W, Affolter, M, Vale, W.W, Izpisua-Belmonte, J.C, Choe, S.
Deposit date:2002-07-03
Release date:2002-12-18
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis of BMP Signalling Inhibition by the Cystine Knot Protein Noggin
Nature, 420, 2002
1NYS
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Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1NYU
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Crystal Structure of Activin A Bound to the ECD of ActRIIB
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1REU
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BU of 1reu by Molmil
Structure of the bone morphogenetic protein 2 mutant L51P
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, bone morphogenetic protein 2
Authors:Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
Deposit date:2003-11-07
Release date:2004-05-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
1REW
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BU of 1rew by Molmil
Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor
Descriptor: bone morphogenetic protein 2, bone morphogenetic protein receptor type IA
Authors:Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
Deposit date:2003-11-07
Release date:2004-05-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.863 Å)
Cite:Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
1S4Y
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BU of 1s4y by Molmil
Crystal structure of the activin/actrIIb extracellular domain
Descriptor: Activin receptor type IIB precursor, Inhibin beta A chain
Authors:Greenwald, J, Vega, M.E, Allendorph, G.P, Fischer, W.H, Vale, W, Choe, S, Joint Center for Structural Genomics (JCSG)
Deposit date:2004-01-19
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-beta Family Receptors.
Mol.Cell, 15, 2004
1TFG
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BU of 1tfg by Molmil
AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
Descriptor: TRANSFORMING GROWTH FACTOR, BETA 2
Authors:Gruetter, M, Schlunegger, M.
Deposit date:1992-11-17
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2.
Nature, 358, 1992
1TGJ
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BU of 1tgj by Molmil
HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
Descriptor: 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-09
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TGK
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HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
Descriptor: TRANSFORMING GROWTH FACTOR BETA 3
Authors:Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
Deposit date:1996-07-10
Release date:1997-03-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1WAQ
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BU of 1waq by Molmil
Crystal structure of human Growth and Differentiation Factor 5 (GDF-5)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GROWTH/DIFFERENTIATION FACTOR 5
Authors:Mueller, T.D, Nickel, J, Sebald, W.
Deposit date:2004-10-27
Release date:2005-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A Single Residue of Gdf-5 Defines Binding Specificity to Bmp Receptor Ib.
J.Mol.Biol., 349, 2005
1ZKZ
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BU of 1zkz by Molmil
Crystal Structure of BMP9
Descriptor: Growth/differentiation factor 2
Authors:Brown, M.A, Zhao, Q, Baker, K.A, Naik, C, Chen, C, Pukac, L, Singh, M, Tsareva, T, Parice, Y, Mahoney, A, Roschke, V, Sanyal, I, Choe, S.
Deposit date:2005-05-04
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure of BMP-9 and functional interactions with pro-region and receptors
J.Biol.Chem., 280, 2005
2ARP
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BU of 2arp by Molmil
Activin A in complex with Fs12 fragment of follistatin
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Follistatin, GLYCEROL, ...
Authors:Harrington, A.E, Morris-Triggs, S.A, Ruotolo, B.T, Robinson, C.V, Ohnuma, S, Hyvonen, M.
Deposit date:2005-08-21
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
2ARV
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BU of 2arv by Molmil
Structure of human Activin A
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, Inhibin beta A chain, ...
Authors:Harrington, A.E, Morris-Triggs, S.A, Ruotolo, B.T, Robinson, C.V, Ohnuma, S, Hyvonen, M.
Deposit date:2005-08-22
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
2ASK
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Structure of human Artemin
Descriptor: SULFATE ION, artemin
Authors:Silvian, L, Jin, P, Carmillo, P, Boriack-Sjodin, P.A, Pelletier, C, Rushe, M, Gong, B.J, Sah, D, Pepinsky, B, Rossomando, A.
Deposit date:2005-08-23
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Artemin crystal structure reveals insights into heparan sulfate binding.
Biochemistry, 45, 2006
2B0U
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The Structure of the Follistatin:Activin Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
Authors:Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2005-09-14
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
2BHK
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Crystal structure of human growth and differentiation factor 5 (GDF5)
Descriptor: GROWTH DIFFERENTIATION FACTOR 5, ISOPROPYL ALCOHOL
Authors:Schreuder, H, Liesum, A, Pohl, J, Kruse, M, Koyama, M.
Deposit date:2005-01-12
Release date:2005-03-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Recombinant Human Growth Differentiation Factor 5. Evidence for Interaction of the Type I and Type II Receptor Binding Sites.
Biochem.Biophys.Res.Commun., 329, 2005

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