2BHK
Crystal structure of human growth and differentiation factor 5 (GDF5)
Summary for 2BHK
Entry DOI | 10.2210/pdb2bhk/pdb |
Related | 1WAQ |
Descriptor | GROWTH DIFFERENTIATION FACTOR 5, ISOPROPYL ALCOHOL (3 entities in total) |
Functional Keywords | growth factor, growth differentiation factor, bone morphogenetic factor, hormone-receptor interaction, cystine knot, preformed receptor dimer, cytokine, dwarfism, glycoprotein |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 13899.11 |
Authors | Schreuder, H.,Liesum, A.,Pohl, J.,Kruse, M.,Koyama, M. (deposition date: 2005-01-12, release date: 2005-03-11, Last modification date: 2023-12-13) |
Primary citation | Schreuder, H.,Liesum, A.,Pohl, J.,Kruse, M.,Koyama, M. Crystal Structure of Recombinant Human Growth Differentiation Factor 5. Evidence for Interaction of the Type I and Type II Receptor Binding Sites. Biochem.Biophys.Res.Commun., 329:1076-, 2005 Cited by PubMed: 15752764DOI: 10.1016/J.BBRC.2005.02.078 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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